IEEE Transactions on
Biomedical Engineering

IEEE Transactions on Biomedical Engineering contains basic and applied papers dealing with biomedical engineering. Papers range from engineering development in methods and techniques with biomedical applications to experimental and clinical investigations with engineering contributions.
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Xiaochuan Pan
Editor-in-chief
Editor-in-chief

"Xiaochuan Pan is currently Professor of Radiology, Radiation & Cellular Oncology, Committee in Medical Physics, the College, and the University of Chicago Medicine Comprehensive Cancer Center at The University of Chicago. He received the BS (1982) and MS (1985) degrees in physics from Beijing University and the Institute of Physics, Science Academy of China and the MS (1988) and PhD (1991) degrees in physics from The University of Chicago. Following post-doc training in medical imaging from 1992-1994 in the Department of Radiology at The University of Chicago, he was appointed as an Assistant Professor of Radiology before being promoted to Associate Professor and Professor of Radiology in 2001 and 2006.

Professor Pan’s research centers on physics, algorithms, and engineering underpinning tomographic imaging and its biomedical and clinical applications. He and his laboratory have conducted research on advanced theory and algorithms for... Read more

"Xiaochuan Pan is currently Professor of Radiology, Radiation & Cellular Oncology, Committee in Medical Physics, the College, and the University of Chicago Medicine Comprehensive Cancer Center at The University of Chicago. He received the BS (1982) and MS (1985) degrees in physics from Beijing University and the Institute of Physics, Science Academy of China and the MS (1988) and PhD (1991) degrees in physics from The University of Chicago. Following post-doc training in medical imaging from 1992-1994 in the Department of Radiology at The University of Chicago, he was appointed as an Assistant Professor of Radiology before being promoted to Associate Professor and Professor of Radiology in 2001 and 2006.

Professor Pan’s research centers on physics, algorithms, and engineering underpinning tomographic imaging and its biomedical and clinical applications. He and his laboratory have conducted research on advanced theory and algorithms for conventional and spectral computed tomography (CT), positron emission tomography (PET), single-photo-emission computed tomography (SPECT), and tomosynthesis especially digital breast tomosynthesis (DBT) and digital lung tomosynthesis (DLT). In collaborating with leading researchers in the field, he and his team have worked on magnetic resonance imaging (MRI) and have also investigated emerging imaging techniques, including electron-paramagnetic resonance imaging (EPRI), phase-contrast CT, and photo-acoustic tomography (PAT), among others. In recent years, he and his team have developed vigorous interest/effort in translating theoretical concepts and methods to biomedical application work that includes developing innovative hardware systems and workflows, enabled by advanced algorithms, with a strong emphasis on the relevance and impact of imaging technological solutions tailored to specific applications of biomedical and/or clinical significance, and have established continuous, close clinical and industrial collaboration and developed robust translational projects to facilitate this effort. Dr. Pan is a Fellow of AAPM, AIMBE, IAMBE, IEEE, OSA, and SPIE."

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IEEE Transactions on

Biomedical Engineering

APRIL 2021
VOLUME 68
NUMBER 4
IEBEAX
68
TBME, Volume 68, Issue 4, April 2021
Performance Evaluation of a Wearable Tattoo Electrode Suitable for High-Resolution Surface Electromyogram Recording
Commercial high-density surface electromyography (HDsEMG) electrodes have limited spatial fidelity, and require electrode paste. As a result, the recorded signals have limited sharpness, inadequate spatial density, and are prone to movement artifacts during muscle contraction. We here demonstrate a novel TATTOO electrode, a dry HDsEMG electrode with a programmable layout. The tattoo electrode is built on stretchable electronics and offers superior skin conformity that can guarantee recording of high-quality HDsEMG signal. We routinely record a larger signal amplitude with higher signal power and occupied bandwidth compared to commercial electrodes. This will potentially enable high-quality recording in clinical applications... Read more
ValveTech: a Novel Robotic Approach for Minimally Invasive Aortic Valve Replacement
The presented surgical robot (called ValveTech) provides a highly controllable instrument for efficient delivery of an artificial valve under integrated endoscopic vision. The flexible manipulator has several features to help the proper valve placement. It provides five degrees of freedom for reaching the operative site via mini-thoracotomy where it adjusts the valve and expands it at the optimal position. The robot was evaluated by ten cardiac surgeons in a simulated surgical scenario: the ValveTech robot proved to be an alternative solution for targeted surgery; improving the quality of the valve implantation both for surgeons and patients... Read more
Evaluation of a Wireless Tongue Tracking System on the Identification of Phoneme Landmarks
Visualizing tongue movement in real-time has the potential to improve therapy outcome for millions of people worldwide living with a speech sound disorder because the positioning of the tongue is crucial in the production of many phonemes to be intelligible. Our team has developed a wearable 3D tongue tracking system based on a wireless magnetic localization method. To evaluate its tracking accuracy, 2,500 tongue trajectories were recorded from 10 subjects uttering 25 phonemes. The results show that our system is capable of tracking tongue motion with positional errors in the order of few millimeters (median: 3.9 mm, Q3: 5.8 mm)... Read more
Infusion Mechanisms in Brain White Matter and its Dependence of Microstructure: An Experimental Study of Hydraulic Permeability
The limited understanding of solute transport in brain white matter tissue has hindered optimisation of infusion-based drug delivery therapies. This paper describes the first direct measurement of hydraulic permeability in white matter subjected to infusion. Our experiments reveal the dependency of hydraulic permeability on the alignment between the flow direction and the orientation of the axonal fibres. This is particularly relevant for the successful development of infusion-based technologies for treatment of lethal tumours in brain, such as convection-enhanced delivery, which are based on the direct injection of drugs under positive pressure into the brain... Read more
Towards 3D ultrasound guided needle steering robust to uncertainties, noise and tissue heterogeneity
This paper presents robust flexible needle steering for robotized punctures guided by 3D ultrasound (US) images. Reaching a target in biological tissue involves being able to detect the inserted needle in the 3D image, to plan a path from its current position and to control motion, at each instant. The proposed approach is able to face the low quality of images, the high variability of biological tissue and the limited ability to capture needle-tissue interactions in a model. Experiments on multi-material phantoms and ex-vivo biological tissue demonstrated the system ability to reach, accurately, US-defined targets using generated 3D helical paths... Read more
CFD Assisted Evaluation of in Vitro Experiments on Bearingless Blood Pumps
The design of modern bearingless blood pumps requires detailed insights of the occurring shear forces within the pump in order to reduce blood damage. As the optimization by means of experimental shear-force analysis is often impractical, this work presents a computational fluid dynamic (CFD) simulation framework, based on Eulerian hemolysis models, to identify the sources of blood damage in bearingless centrifugal pumps. The outputs obtained with this framework are compared to experimental hemolysis tests conducted with ten different pump prototypes. As a result, this work provides design guidelines for improving the cell compatibility of future centrifugal blood pumps... Read more