IEEE Transactions on
Biomedical Engineering

IEEE Transactions on Biomedical Engineering contains basic and applied papers dealing with biomedical engineering. Papers range from engineering development in methods and techniques with biomedical applications to experimental and clinical investigations with engineering contributions.
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Xiaochuan Pan
Editor-in-chief
Editor-in-chief

"Xiaochuan Pan is currently Professor of Radiology, Radiation & Cellular Oncology, Committee in Medical Physics, the College, and the University of Chicago Medicine Comprehensive Cancer Center at The University of Chicago. He received the BS (1982) and MS (1985) degrees in physics from Beijing University and the Institute of Physics, Science Academy of China and the MS (1988) and PhD (1991) degrees in physics from The University of Chicago. Following post-doc training in medical imaging from 1992-1994 in the Department of Radiology at The University of Chicago, he was appointed as an Assistant Professor of Radiology before being promoted to Associate Professor and Professor of Radiology in 2001 and 2006.

Professor Pan’s research centers on physics, algorithms, and engineering underpinning tomographic imaging and its biomedical and clinical applications. He and his laboratory have conducted research on advanced theory and algorithms for... Read more

"Xiaochuan Pan is currently Professor of Radiology, Radiation & Cellular Oncology, Committee in Medical Physics, the College, and the University of Chicago Medicine Comprehensive Cancer Center at The University of Chicago. He received the BS (1982) and MS (1985) degrees in physics from Beijing University and the Institute of Physics, Science Academy of China and the MS (1988) and PhD (1991) degrees in physics from The University of Chicago. Following post-doc training in medical imaging from 1992-1994 in the Department of Radiology at The University of Chicago, he was appointed as an Assistant Professor of Radiology before being promoted to Associate Professor and Professor of Radiology in 2001 and 2006.

Professor Pan’s research centers on physics, algorithms, and engineering underpinning tomographic imaging and its biomedical and clinical applications. He and his laboratory have conducted research on advanced theory and algorithms for conventional and spectral computed tomography (CT), positron emission tomography (PET), single-photo-emission computed tomography (SPECT), and tomosynthesis especially digital breast tomosynthesis (DBT) and digital lung tomosynthesis (DLT). In collaborating with leading researchers in the field, he and his team have worked on magnetic resonance imaging (MRI) and have also investigated emerging imaging techniques, including electron-paramagnetic resonance imaging (EPRI), phase-contrast CT, and photo-acoustic tomography (PAT), among others. In recent years, he and his team have developed vigorous interest/effort in translating theoretical concepts and methods to biomedical application work that includes developing innovative hardware systems and workflows, enabled by advanced algorithms, with a strong emphasis on the relevance and impact of imaging technological solutions tailored to specific applications of biomedical and/or clinical significance, and have established continuous, close clinical and industrial collaboration and developed robust translational projects to facilitate this effort. Dr. Pan is a Fellow of AAPM, AIMBE, IAMBE, IEEE, OSA, and SPIE."

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Featured Articles

IEEE Transactions on

Biomedical Engineering

JUNE 2021
VOLUME 68
NUMBER 6
IEBEAX
68
TBME, Volume 68, Issue 6, June 2021
Transcranial Focused Ultrasound Neuromodulation of Voluntary Movement-related Cortical Activity in Humans
Low-intensity transcranial focused ultrasound (tFUS) is a non-invasive brain stimulation tool for reversibly modulating brain circuits. How the tFUS influences the human voluntary motor processing in the brain remains unclear. We applied the tFUS to modulate the movement-related cortical potential (MRCP) originating from human subjects practicing a voluntary foot tapping task. The MRCP source was reconstructed and evaluated for assessing the tFUS neuromodulatory effects on the voluntary MRCP. The effect of ultrasound pulse repetition frequency was further assessed in modulating the MRCP. This work provides the first evidence of tFUS enhancing the human endogenous motor cortical activities through excitatory modulation... Read more
Portable Automatic Micro-Ring Resonator System Using a Subwavelength Grating Metamaterial Waveguide for High-Sensitivity Real-Time Optical-Biosensing Applications
As the needs for bio-related detections continue to intensify in the healthcare industry due to the COVID-19 pandemic, our work on Si-microring slow-light systems comes as a timely aide with its small size, fast screening, and early diagnosis capabilities. The presented portable system integrates Si photonics with automated mechanical configurations in a platform that provides faster and real-time readouts, higher sensitivities, all working within the optical telecommunication bands, and ready for portable remote area point-of-care applications. With different receptors immobilized on the chip surface, it is also good for open applications in heavy metal detection, virus examination, and cancer diagnosis... Read more
Design and Preliminary Assessment of a Passive Elastic Leg Exoskeleton for Resistive Gait Rehabilitation
While devices that assist walking can enable individuals with neuromusculoskeletal impairments, recovery is often better facilitated by devices that resist walking. Moreover, current robotic interfaces for gait rehabilitation are typically huge, bulky, and come with a large price tag. This article describes the design and development of a novel, wearable, passive elastic exoskeleton for resistive gait rehabilitation. The system uses counteracting compressional springs, pulleys, and clutches and can be configured to resist flexion, extension, or bidirectionally. Thus, the device can target user-specific muscle weaknesses and accommodate range of motion limitations. These concepts were validated using benchtop and human subject experiments... Read more
Modeling of Interstitial Ultrasound Ablation for Continuous Applicator Rotation with MR Validation
Predictive modeling can play an important role in thermal ablative cancer treatments where estimated energy deposition may integrate into pre-operative planning software or combine with closed loop control. In this work, we develop a finite element model capable of simulating continuous rotation by a directional interstitial ultrasound applicator. The developed model simulates temperature maps for different rotation trajectories. The developed simulation was validated using magnetic resonance thermal imaging and demonstrated performance suitable for real-time control of robotically actuated conformal tumor ablation... Read more
Hybrid Tongue – Myoelectric Control Improves Functional Use of a Robotic Hand Prosthesis
To achieve increased clinical impact with myoelectric upper limb prostheses, control schemes need to effectively perform different grasping actions and simple manipulation tasks enabling the execution of Activities of Daily Living (ADL). In this comparative study we demonstrate, that a control scheme allowing for direct activation of grasps using a tongue interface, and proportional control of opening and closing using two EMG signals, can be an attractive method for providing enhanced control of multifunctional prosthetic hands. This was shown using functional evaluation focusing on the completion of ADL tasks characterised by bimanual activities, which are particularly challenging for prostheses users... Read more
Flexible, Air Dryable, and Fiber Modified Aerogel-Based Wet Electrode for Electrophysiological Monitoring
This study presents a novel type of wet electrode material for electrophysiological monitoring based on a conductive aerogel film. The electrode material incorporates cellulose nanocrystal and fiber as a biocompatible polymer and multi-walled carbon nanotube as a conductive filler. The wet aerogel film presents suitable mechanical flexibility and a high water absorption due to the porosity of the film and hydrophilicity of the base polymer allowing it for effective wet electrode applications. The electrical impedance range of the fabricated aerogel electrodes is within the range of use for various electrophysiological monitoring purposes such as electrocardiography (ECG) and electroencephalography (EEG)... Read more