IEEE Transactions on
Biomedical Engineering

IEEE Transactions on Biomedical Engineering contains basic and applied papers dealing with biomedical engineering. Papers range from engineering development in methods and techniques with biomedical applications to experimental and clinical investigations with engineering contributions.
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Xiaochuan Pan
Editor-in-chief
Editor-in-chief

"Xiaochuan Pan is currently Professor of Radiology, Radiation & Cellular Oncology, Committee in Medical Physics, the College, and the University of Chicago Medicine Comprehensive Cancer Center at The University of Chicago. He received the BS (1982) and MS (1985) degrees in physics from Beijing University and the Institute of Physics, Science Academy of China and the MS (1988) and PhD (1991) degrees in physics from The University of Chicago. Following post-doc training in medical imaging from 1992-1994 in the Department of Radiology at The University of Chicago, he was appointed as an Assistant Professor of Radiology before being promoted to Associate Professor and Professor of Radiology in 2001 and 2006.

Professor Pan’s research centers on physics, algorithms, and engineering underpinning tomographic imaging and its biomedical and clinical applications. He and his laboratory have conducted research on advanced theory and algorithms for... Read more

"Xiaochuan Pan is currently Professor of Radiology, Radiation & Cellular Oncology, Committee in Medical Physics, the College, and the University of Chicago Medicine Comprehensive Cancer Center at The University of Chicago. He received the BS (1982) and MS (1985) degrees in physics from Beijing University and the Institute of Physics, Science Academy of China and the MS (1988) and PhD (1991) degrees in physics from The University of Chicago. Following post-doc training in medical imaging from 1992-1994 in the Department of Radiology at The University of Chicago, he was appointed as an Assistant Professor of Radiology before being promoted to Associate Professor and Professor of Radiology in 2001 and 2006.

Professor Pan’s research centers on physics, algorithms, and engineering underpinning tomographic imaging and its biomedical and clinical applications. He and his laboratory have conducted research on advanced theory and algorithms for conventional and spectral computed tomography (CT), positron emission tomography (PET), single-photo-emission computed tomography (SPECT), and tomosynthesis especially digital breast tomosynthesis (DBT) and digital lung tomosynthesis (DLT). In collaborating with leading researchers in the field, he and his team have worked on magnetic resonance imaging (MRI) and have also investigated emerging imaging techniques, including electron-paramagnetic resonance imaging (EPRI), phase-contrast CT, and photo-acoustic tomography (PAT), among others. In recent years, he and his team have developed vigorous interest/effort in translating theoretical concepts and methods to biomedical application work that includes developing innovative hardware systems and workflows, enabled by advanced algorithms, with a strong emphasis on the relevance and impact of imaging technological solutions tailored to specific applications of biomedical and/or clinical significance, and have established continuous, close clinical and industrial collaboration and developed robust translational projects to facilitate this effort. Dr. Pan is a Fellow of AAPM, AIMBE, IAMBE, IEEE, OSA, and SPIE."

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Featured Articles

IEEE Transactions on

Biomedical Engineering

SEPTEMBER 2020
VOLUME 67
NUMBER 9
IEBEAX
67
TBME, Volume 67, Issue 9, September 2020
Millimeter-wave Substrate Integrated Waveguide Probe for Skin Cancer Detection
This work presents an innovative, low-cost, easy-to-fabricate, and simple-to-use probe that can detect early-stage skin cancer. As can be seen above, the probe scans the suspected skin area to enable capturing the reflection coefficient at each position. The collected data is then processed to infer the presence of skin cancer through a differential approach. In order to do this, a novel imaging function is utilized to enable the detection of relative permittivity changes with respect to the healthy region surrounding the suspected one, resulting in the 2D image depicted above... Read more
Compact Optical Neural Probes with up to 20 Integrated Thin-Film μLEDs Applied in Acute Optogenetic Studies
Slender silicon-based optical probes comprising up to 20 thin-film micro light-emitting diodes (µLEDs) are realized as compact devices for optogenetic research. The μLEDs are structured on GaN-on-sapphire and transferred onto silicon using a wafer-level bonding and laser lift-off process. This technology allows processing the GaN layer stack from both sides, thereby maximizing the µLED efficiency to an emittance of 56 mWmm−2 at 5 mA. The thermal characterization of the optical probes reveals a temperature increase of up to 1.5 K. Acceptable neuronal responses are elicited at radiant flux values between 1.36 μW and 17.5 μW, successfully demonstrating layer-specific cortex stimulation... Read more
A System for Characterizing Intraoperative Force Distribution during Operative Laryngoscopy
Investigators are increasingly finding that “smart” surgical instrumentation may improve clinical outcomes as greater tool-tissue contact forces are correlated with peri- and post-operative complications. While previous efforts to study intraoperative pressure distributions in otolaryngology have been limited by static equilibrium assumptions and cadaver-only testing, we present an integrated data acquisition system for detecting intraoperative forces and pressures during operative laryngoscopy using sixteen piezoresistive sensors. This low-cost and custom system can be calibrated within one hour prior to procedure with 1–2.5% error, and cadaver and live patient trials have shown comparable force and pressure data to literature values... Read more
Computed Tomography-Based Modeling of Water Vapor-Induced Changes in Permittivity During Microwave Ablation
One can imagine that boiling water has such different physical properties than drinking water. Microwave ablation, a minimally invasive cancer treatment modality, increases the temperature of tissues even higher than the boiling temperature of water to eradicate cancerous tissues. To achieve an accurate simulation for microwave ablation treatment planning, we need to consider all the changes that occur in tissue properties. In this study, we used computed tomography imaging to measure the amount of water vapor that accumulates in tissues during microwave ablation. We modeled tissue properties as a function of vapor content using mixture equations which possessed greater accuracy than existing models... Read more
Simultaneous Optimization of Patient–Image Registration and Hand–Eye Calibration for Accurate Augmented Reality in Surgery
For augmented reality (AR)-guided endoscopic surgery, patient–image registration and hand–eye calibration are essential steps and they have been separately performed so far with accumulating errors. In the proposed method, the two separate steps are integrated in a single step with minimized errors under the on-site AR condition. The AR superimposing accuracy can increase due to the reduced computational complexity of transformation processes and the compensated tracking errors of the position sensor…... Read more
Disposable Paper-on-CMOS Platform for Real-time Simultaneous Detection of Metabolites
A fast and simple-to-use platform that combines an integrated circuit with paper microfluidics for simultaneous detection of multiple-metabolites appropriate for diagnostics is presented. The system measures changes in optical absorbance in functionalised paper to achieve a cost-effective and easy to implement system that is capable of multiple simultaneous assays. Potential sepsis metabolite biomarkers, glucose, and lactate, have been studied with the platform, achieving sensitivity within the physiological range in human serum. The combination of a low-cost paper strip and sensitive CMOS photodiodes makes our platform a robust, portable, and inexpensive biosensing device for multiple diagnostic tests in many applications... Read more