Blood perfusion plays a key role for the ablation success, especially in the case of highly vascularized organs like liver. Aim of this work is to evaluate the vessel distance influence on the thermal gradient and the cooling of the tissue caused by blood perfusion during laser ablation. The proposed setup, based on Fiber Bragg Grating sensors (FBGs) around the laser applicator, permitted to measure the heat propagation and to observe a relevant tissue cooling near to the vessel... Read more

Deep brain stimulation (DBS) is an effective therapy for Parkinson’s disease (PD). The success of the procedure depends heavily on the accurate placement of the electrode within the optimal therapeutic targets while avoiding vital structures that can cause adverse outcomes. Interventional guidance with medical imaging has greatly contributed to the development, outcomes, and safety of the procedure. With rapid technological advancements, it will further enhance the capacity and efficacy of the procedure. We present a comprehensive review on the state-of-the-art techniques in image-guided DBS surgery to treat PD, and discuss about the future directions on the topic... Read more

Alzheimer’s disease (AD) is a chronic neurodegenerative disease, and its long-term progression prediction is definitely important. The structural Magnetic Resonance Imaging (sMRI) can be used to characterize the cortical atrophy that is closely coupled with clinical symptoms in AD and... Read more