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May 2021
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The Brain on COVID-19
In March 2020 —still the early days of the U.K.’s COVID-19 crisis—Rhys Thomas, a neurologist at Newcastle University, got a call at home from a concerned colleague. The colleague’s cousin was hospitalized, critically ill with COVID-19, and had developed brainstem encephalitis, a severe inflammatory condition of the brain causing a suite of symptoms, from eye problems to balance problems and drowsiness. He wanted to know if Thomas knew anything about these conditions. At the time, the research coming out of Wuhan, China, only suggested a mild whiff of neurological ­symptoms—headache, dizziness, and the loss of taste and smell... Read more

New Vaccine-Manufacturing Methods Are Moving Away From the Egg
With seasonal influenza, Ebola, shingles, pneumonia, human papillomavirus, and other pathogens—combined now with the novel coronavirus (SARS-CoV-2)—the world’s demand for vaccines is on a steep incline. New vaccine development is progressing rapidly, as seen with recent announcements of coronavirus options [1], [2], but what about their manufacture?... Read more
Versatile Graphene Underlies New COVID-Zapping Air Filter
Researchers have developed new ways to use the extremely versatile material graphene, and a company is now building on that work to manufacture an air-filtration device that kills bacteria and viruses—including the virus responsible for coronavirus disease 2019 (COVID-19)—on contact... Read more
A Step Closer to Mind Control for Everyday Life
Brain–computer interface (BCI) technology holds promise for providing functional support systems for people with neurological disorders and other disabilities. In experimental laboratory settings, BCIs have allowed patients to communicate with researchers and control external devices—all by simply imagining the actions of different body parts... Read more
Understanding the Long-Term Impacts of COVID-19 in Survivors
In mid-March 2020, as the novel coronavirus started making its way through the United States, Fiona Lowenstein (they/their) became ill. At that point, there was not yet any public health guidance on social distancing and wearing masks, and certainly no routine or readily accessible testing for COVID-19. Lowenstein was still interacting with others in person, and even led a yoga class. But when they became sick and were hospitalized, they were tested for SARS-CoV2 and received a positive diagnosis... Read more
Solving Unmet Needs With Innovative Pediatric Medical Devices
In the last decade, only 24% of class III life-saving devices approved by the U.S. Food and Drug Administration (FDA) were for pediatric use—and most of those were for children over 12. Of these, less than 4% were labeled for pediatric patients ages 0–2 years old and the number of approved devices is even lower for neonatal patients. For these young patients, adult medical devices are often manipulated by pediatric specialists in order to provide stop-gap solutions. However, these repurposed devices are not always able to fulfill the unique needs of children’s biology and growth patterns... Read more

Journal Updates

IEEE Transactions on

Biomedical Engineering

MARCH 2021
TBME, Volume 68, Issue 3, March 2021
Fiber optic sensors-based thermal analysis of perfusion-mediated tissue cooling in liver undergoing laser ablation
Blood perfusion plays a key role for the ablation success, especially in the case of highly vascularized organs like liver. Aim of this work is to evaluate the vessel distance influence on the thermal gradient and the cooling of the tissue caused by blood perfusion during laser ablation. The proposed setup, based on Fiber Bragg Grating sensors (FBGs) around the laser applicator, permitted to measure the heat propagation and to observe a relevant tissue cooling near to the vessel... Read more
Image guidance in deep brain stimulation surgery to treat Parkinson’s disease: a comprehensive review
Deep brain stimulation (DBS) is an effective therapy for Parkinson’s disease (PD). The success of the procedure depends heavily on the accurate placement of the electrode within the optimal therapeutic targets while avoiding vital structures that can cause adverse outcomes. Interventional guidance with medical imaging has greatly contributed to the development, outcomes, and safety of the procedure. With rapid technological advancements, it will further enhance the capacity and efficacy of the procedure. We present a comprehensive review on the state-of-the-art techniques in image-guided DBS surgery to treat PD, and discuss about the future directions on the topic... Read more
IEEE Journal of

Biomedical And Health Informatics

MARCH 2021
The IEEE Journal of Biomedical And Health Informatics Volume 25, Issue 3 has been published.
Prediction of Alzheimer’s Disease Progression with Multi-Information Generative Adversarial Network
Alzheimer’s disease (AD) is a chronic neurodegenerative disease, and its long-term progression prediction is definitely important. The structural Magnetic Resonance Imaging (sMRI) can be used to characterize the cortical atrophy that is closely coupled with clinical symptoms in AD and... Read more