The mRNA Revolution is Coming
A bright spot during this COVID-19 pandemic has been the rapid development of effective vaccines that work by harnessing the power of messenger RNA, or mRNA. mRNA vaccines might seem like a relatively new idea, but researchers have been working on the technology behind them for decades. Now, the success of Moderna and Pfizer’s coronavirus vaccines are highlighting the immense potential for mRNA therapies—not just for infectious diseases, but also to treat cancer and genetic disorders... Read more

Looking Disease in the Eye
From eye disease to neurological conditions, new technologies are making earlier diagnosis and better patient outcomes a reality by investigating the eye... Read more
Easing Burnout in Health Care
As the pandemic continues to overwhelm hospitals and staff, mobile strategies to address mental health strain among health care workers are becoming more readily available... Read more
Biomedical Innovation for Everyone, Bias-Free
When undergraduate student Arnelle Etienne (Figure 1) joined a research group at Carnegie Mellon University (CMU), Pittsburgh, PA, USA, to help with the development of electroencephalograph (EEG) electrodes, her first task was to do some background work and learn about them. What she found was both surprising and dismaying: EEG electrodes had never worked—and still did not work on—a large segment of the population; and clinicians and researchers knew about the oversight... Read more
A Life Well Lived: In Memory of Máximo E. Valentinuzzi
This article is dedicated to the memory of Max E. Valentinuzzi, an IEEE EMBS Life Fellow and Argentinian biomedical engineer of unparalleled achievements and special contributions to this magazine. Dr. Valentinuzzi passed away on 3 January 2021... Read more
AI, Virtual Reality, and Robots Advancing Autism Diagnosis and Therapy
Autism spectrum disorder (ASD) is a challenge in multiple ways. Just getting diagnosed can take months of visits to doctors and specialists. After the diagnosis, children are often put on long waiting lists to begin therapy, which itself consists of frequent sessions that while helpful, are usually quite taxing for both the children and their parents. And while child-directed therapies are available, adults who are on the spectrum often find little continuing support. Recent technologies are using artificial intelligence (AI), machine learning (ML), virtual reality (VR), and other advanced methods to address all of those issues with faster and easier diagnostics, and in-home therapeutic approaches designed for all ages... Read more
COVID-19 and Cardiovascular Health
In late February 2020, a time when severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2, or COVID-19) still felt like an abstraction in the United States, New York City’s first infected patient was admitted to Mount Sinai Hospital’s emergency room. Working a few doors down was Sean Pinney, the Director of Advanced Heart Failure and Transplantation. Little did he know, but “that night was the beginning of hell,” he said... Read more
Innovative Vaccines to Fight COVID-19, Other Viruses
COVID-19 added urgency to the quest for the development of new vaccines, and academic researchers and biotechnology companies responded by capitalizing on already-in-the-pipeline advances and swiftly transitioning products from the lab to the clinic. Their efforts reaped rewards. According to a U.S. Department of Health and Human Services analysis, the COVID vaccines delivered in the USA from January to May 2021 resulted in 39,000 fewer deaths and 107,000 fewer hospitalizations, and prevented another 265,000 cases among Medicare recipients alone... Read more

EMBS Journal Updates

The IEEE Transactions on Neural Systems and Rehabilitation Engineering Volume 29 has been published.
Transactions on

Neural Systems and Rehabilitation Engineering

Continuous Gait Phase Estimation using LSTM for Robotic Transfemoral Prosthesis Across Walking Speeds
User gait phase estimation plays a key role for the seamless control of the lower-limb robotic assistive devices (e.g., exoskeletons or prostheses) during ambulation. To achieve this, several studies have attempted to estimate the gait phase using a thigh or... Read more
Eye Blink Artifact Detection with Novel Optimized Multi-dimensional Electroencephalogram Features
Accurate eye blink artifact detection is essential for electroencephalogram (EEG) analysis and auxiliary analysis of nervous system diseases, especially in the presence of the frontal epileptiform discharges. In this paper, we develop a novel eye blink artifact detection algorithm based... Read more

Pulse Ideas

State of the Art November/December 2021
Alone With My Thoughts
They call them earworms, those songs and ditties that roll around in your head whenever there is nothing else going on. Even when you want to be alone, they are always there, whether one wants them or not. And they resist being forgotten. Some are simple little things, jingles that keep ringing in my ears all day and all night long. They can be triggered by some simple reminder, like catching a television or radio ad, hearing children singing familiar songs, or listening to a choir sing a catchy gospel melody. “It’s A Small World” is particularly deadly... Read more
Book Reviews November/December 2021
Electronic Devices, Circuits, and Systems for Biomedical Applications: Challenges and Intelligent Approach, 1st ed.
This 25-chapter text is the product of some 73 contributors, as edited by five editors. Publicity for the text suggests the book “explains the latest information on the design of new technological solutions for low-power, high-speed efficient biomedical devices, circuits and systems” and is “is ideal for graduate students in biomedical engineering and medical informatics, biomedical engineers, medical device designers, and researchers in signal processing.” After reading the first nine chapters of this text (plus a tenth), this review suggests that this text falls short of the above aspirations. The reasons why will become evident in the chapter reviews below... Read more
Senior Design September/October 2021
Updating Design Faculty Industry Experience
Most biomedical engineering students around the country will eventually end up working for a medical device company. For this reason, biomedical engineering capstone design courses should not only provide students with a hands-on design experience, but they should also prepare students for careers in the medical device industry. These courses should be relevant and up to date to reflect current design trends, processes, and practices followed in industry... Read more
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