Blood perfusion

Multimodal Imaging of Laser Speckle Contrast Imaging Combined with Mosaic Filter-Based Hyperspectral Imaging for Precise Surgical Guidance

Author(s): Sanghwa Lee, Jung-Man Namgoong, Youngkyu Kim, Jaepyeong Cha, Jun Ki Kim
Multimodal Imaging of Laser Speckle Contrast Imaging Combined with Mosaic Filter-Based Hyperspectral Imaging for Precise Surgical Guidance 170 177 IEEE Transactions on Biomedical Engineering (TBME)
The goal of this study is to develop a multi-modality imaging system combining visible, hyperspectral imaging (HSI), and laser speckle contrast imaging (LSCI) to guide surgical procedures for organ transplantation and resection. Resection sites are specified through high-resolution general imaging and LSCI, which makes blood perfusion observable without labels or contrast agents. Tissues are classified by HSI of hemodynamic biomarkers. The multimodal device is capable of monitoring oxygen saturation from the spectral changes characteristic of blood to detect thrombosis, perfusion, and hemorrhage. Based on these technologies, the risks to patients in the operating room can be minimized. read more

Fiber optic sensors-based thermal analysis of perfusion-mediated tissue cooling in liver undergoing laser ablation

Author(s): Elena De Vita, Martina De Landro, Carlo Massaroni, Agostino Iadicicco, Paola Saccomandi, Emiliano Schena, Stefania Campopiano
Fiber optic sensors-based thermal analysis of perfusion-mediated tissue cooling in liver undergoing laser ablation 170 177 IEEE Transactions on Biomedical Engineering (TBME)
Blood perfusion plays a key role for the ablation success, especially in the case of highly vascularized organs like liver. Aim of this work is to evaluate the vessel distance influence on the thermal gradient and the cooling of the tissue caused by blood perfusion during laser ablation. The proposed setup, based on Fiber Bragg Grating sensors (FBGs) around the laser applicator, permitted to measure the heat propagation and to observe a relevant tissue cooling near to the vessel. read more