Development of Dopamine Sensor Using Silver Nanoparticles and PEG Functionalized Tapered Optical Fiber Structure
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IEEE Transactions on Biomedical Engineering (TBME)
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A medical diagnosis of dopamine used one of the most effective localized surface plasmon resonance (LSPR) optical methods in this study. LSPR technology has many unique features such as real-time monitoring, label-free detection, and smooth integration. Sensor is immobilized with silver-nanoparticles followed by functionalization of polyethylene glycol. Highly sophisticated instruments such as HR-TEM, UV-Vis-spectrophotometer, EDS, and SEM were used for the characterization of nanoparticles and immobilized probe. It shows the great selectivity towards detection of dopamine in the presence of other higher concentrated coexist biomolecules such as ascorbic acid. A noticeable improvement is recorded in the all-important sensing parameters.
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