In Vitro – In Vivo Drug Release Xylitol

Development of a Chewing Robot with Built-in Humanoid Jaws to Simulate Mastication to Quantify Robotic Agents Release from Chewing Gums Compared to Human Participants

Author(s)3: Kazem Alemzadeh, Sian Bodfel Jones, Maria Davies, Nicola West
Development of a Chewing Robot with Built-in Humanoid Jaws to Simulate Mastication to Quantify Robotic Agents Release from Chewing Gums Compared to Human Participants 170 107 IEEE Transactions on Biomedical Engineering (TBME)
Medicated chewing gum has been recognised as a new advanced drug delivery method. Its potential has not yet been fully exploited because currently there is no gold standard for testing the gum in vitro. This study presents a novel humanoid chewing robot could provide opportunities for pharmaceutical companies to investigate and refine drug release from gum, with reduced patient exposure and costs. read more