Ranjan K Dash
Ranjan K Dash is an Associate Professor in the Department of Physiology and Biotechnology and Bioengineering Center at the Medical College of Wisconsin. He received his Ph.D. degree in Applied Mathematics, specializing in Computational Biofluid Dynamics from the Indian Institute of Technology Delhi in July 1998, before moving to the USA for postdoctoral studies. He has published more than 65 papers in peer-reviewed scientific journals covering a wide range of research areas. His current research interests are focused on developing computational models in conjunction with experimental data to understand the underlying molecular mechanisms of cardiac ischemia and reperfusion (IR) injury and related pathologies.
JTEHM, Articles, Published ArticlesOptical Cryoimaging Reveals a Heterogeneous Distribution of Mitochondrial Redox State in ex vivo Guinea Pig Hearts and its Alteration during Ischemia and Reperfusion
Mahsa Ranji, Mohammad Masoudi Motlagh, Fahimeh Salehpour, Reyhaneh Sepehr, James S. Heisner, Ranjan K Dash, Amadou KS Camara
Objective: Oxidation of substrates to generate ATP in mitochondria is mediated by redox reactions of NADH and FADH2. Cardiac ischemia and reperfusion (IR) injury compromises mitochondrial oxidative phosphorylation. We hypothesize that IR alters the metabolic heterogeneity of mitochondrial redox state... Read more
Posted on 30 JUN 2016