Dong Sun

Mechanical and Biomedical Engineering, City University of Hong Kong, Hong Kong China HK

Associated articles

TBME, Featured Articles
Characterization of a Honeycomb-like Scaffold with Dielectrophoresis-based Patterning for Tissue Engineering
Seeding and patterning of cells with an engineered scaffold is a critical process in artificial tissue construction and regeneration. To date, many engineered scaffolds exhibit simple intrinsic designs, which fail to mimic the geometrical complexity of native tissues. In this... Read more
TBME, Featured Articles
Achieving Automated Organelle Biopsy on Small Single Cells Using a Cell Surgery Robotic System
       Studies on bulk tissues only provide a statistical average of several actions taken place in different cells. Single cell investigation may disclose further important and in-depth information. Single cell surgery such as manipulation or removal of subcellular components or/and organelles... Read more
TBME, Featured Articles
Combined Single Cell Manipulation and Chemomechanical Modeling to Probe Cell Migration Mechanism during Cell-to-cell Interaction
During cell-to-cell interaction, spatial presentations of chemical and mechanical information are key parameters for cell migration. A chemomechanical model to assess the biochemical and biophysical modulators of single cell migration during cell-to-cell interaction can help to understand cell migration in a complex environment that is close to realistic in vivo situation. In the work, the issue is modeled based on molecular clutches, and experiment validation is implemented through single cell manipulation through optical tweezers. The results show that cell migration velocity caused by chemotaxis can be biased by dynamic adhesion force between cells... Read more
TBME, Featured Articles
Automated In Vivo Navigation of Magnetic-Driven Microrobots Using OCT Imaging Feedback
This paper presents a study on the navigation of microrobots in vivo by using optical coherence tomography (OCT) imaging feedback. The electromagnetic gradient field generated by a home-made electromagnetic manipulation system is magnetically modeled. With this model, the magnetic force acting on the microrobot is calculated, and the relationship between this force and the velocity of the microrobot is characterized. The findings are verified by the in vitro and in vivo environments, with the imaging feedback of the OCT imaging system and the actuation of the electromagnetic manipulation system. Experimental results have successfully demonstrated the effectiveness of the proposed approach... Read more