Transactions on

NanoBioscience

The IEEE Transactions on NanoBioscience publishes basic and applied papers dealing both with engineering, physics, chemistry, modeling and computer science and with biology and medicine with respect to molecules, cells, tissues. The content of acceptable papers ranges from practical/clinical/environmental applications to formalized mathematical theory.

Editor-in-Chief

Dan V. Nicolau, Ph.D.

Dan V. Nicolau, Ph.D.

Dan has degrees in Chemical Engineering (PhD, MEng) and in Statistics, Cybernetics & Information Technology (MSc). His research covers biocomputation and biosimulation, nanodevices powered by protein molecular motors, surface science and engineering, micro- and nano-fabrication for semiconductor and biomedical devices, process modelling and control, and protein adsorption. Dan is a Professor of Bioengineering with McGill University, the Maria Zelenka-Roy Chair in Bioengineering, and the founding Chair of McGill’s Department of Bioengineering in the Faculty of Engineering. Dan authored more than 200 peer-reviewed publications, co-edited a book, and chaired more than 30 international conferences. He has been the Editor-in-Chief of the IEEE Transactions on NanoBioscience since January 1, 2020.

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TNB Top Reviewer 2020

Dr. Uche Chude-Okonkwo

Dr. Uche Chude-Okonkwo

IEEE TNB Top Reviewer 2020

June Issue Editor’s Choice

Quantum Speedup and Mathematical Solutions from Implementing Bio-molecular Solutions for the Independent Set Problem on IBM’s Quantum Computers

In this paper, we propose a bio-molecular algorithm with O(n2 + m) biological operations, O(2n) DNA strands, O(n) tubes and the longest DNA strand, O(n), for solving the independent-set problem for any graph G with m edges and n vertices. Next, we show that a new kind of the straightforward Boolean circuit yielded from the bio-molecular solutions with m NAND gates, (m + n × (n +1)) AND gates and ((n × (n + 1)) / 2) NOT gates can find the maximal independent-set(s) to the independent-set problem for any graph G with m edges and n vertices. We show that a new kind of the proposed quantum-molecular algorithm can find the maximal independent set(s) with the lower bound O(2n/2) queries and the upper bound Ω(2n/2) queries. This work offers an obvious evidence that to solve the independent-set problem in any graph G with m edges and n vertices, bio-molecular computers are able to generate a new kind of the straightforward Boolean circuit such that by means of implementing it quantum computers can give a quadratic speed-up. This work also offers one obvious evidence that quantum computers can significantly accelerate the speed and enhance the scalability of bio-molecular computers. Furthermore, to justify the feasibility of the proposed quantum-molecular algorithm, we successfully solve a typical independent set problem for a graph G with three vertices and two edges by carrying out experiments on the backend ibmqx4 with five quantum bits and the backend simulator with 32 quantum bits on IBM’s quantum computer.

Updates

Space-Dividing-Based Cluster Synchronization of Reaction-Diffusion Genetic Regulatory Networks via Intermittent Control 758 343 Transactions on NanoBioscience (TNB)

Space-Dividing-Based Cluster Synchronization of Reaction-Diffusion Genetic Regulatory Networks via Intermittent Control

Author(s): Xiaona Song, Xingru Li, Choon Ki Ahn, Shuai Song

In this paper, we focus on the cluster synchronization of reaction-diffusion genetic regulatory networks (RDGRNs) with time-varying delays, where the state of the system is not only time-dependent but also…

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Multi-Analyte Detection Based on Integrated Internal and External Sensing Approach 439 520 Transactions on NanoBioscience (TNB)

Multi-Analyte Detection Based on Integrated Internal and External Sensing Approach

Author(s): Firoz Haider, Md. Mashrafi, Rifat Ahmmed Aoni, Rakib Haider, Moqbull Hossen, Tanvir Ahmed, Ghafour Amouzad Mahdiraji, Rajib Ahmed

Highly sensitive, simple and multiplex detection capabilities are key criteria of point-of-care (POC) diagnosis in clinical samples. Here, a simple and highly sensitive multi-analyte detection technique is proposed by using…

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Solving the Family Traveling Salesperson Problem in the Adleman-Lipton model based on DNA computing 457 373 Transactions on NanoBioscience (TNB)

Solving the Family Traveling Salesperson Problem in the Adleman-Lipton model based on DNA computing

Author(s): Xian Wu, Zhao Cai Wang, Tun Hua Wu, Xiao Guang Bao

The Family Traveling Salesperson Problem (FTSP) is a variant of the Traveling Salesperson Problem (TSP), in which all vertices are divided into several different families, and the goal of the…

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A High-voltage TENG-based Droplet Energy Generator with Ultralow Liquid Consumption 906 360 Transactions on NanoBioscience (TNB)

A High-voltage TENG-based Droplet Energy Generator with Ultralow Liquid Consumption

Author(s): Da-Jeng Yao, Hsuan-Yu Lin, Ting-Wei Wang, Zong-Hong Lin

A solid-liquid triboelectric nanogenerator (TENG) has attracted increasing research interest in relation to the development of regeneration energy based on water resources. The output of solid-liquid TENG remains unsolved, however,…

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Synthesis of α,β-unsaturated benzotriazolyl-1,3,4-oxadiazole derivatives: anticancer activity, cytotoxicity, and cell imaging 940 413 Transactions on NanoBioscience (TNB)

Synthesis of α,β-unsaturated benzotriazolyl-1,3,4-oxadiazole derivatives: anticancer activity, cytotoxicity, and cell imaging

Author(s): Eugenio Hernández-Fernández, Juany C. Nava-Ramírez, Silvia Elena Santana-Krímskaya, Moisés Armides Franco-Molina, Ana Sofia Ortega-Villarreal, Israel López, David J. Michaelis

A series of ten α,β-unsaturated benzotriazolyl-1,3,4-oxadiazole derivatives was synthesized and all compounds were evaluated in vitro against three breast cancer cell lines (MCF-7, MDA-MB-231 and 4T1) at different concentrations (0.1,…

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Adaptive Parameter Model for Quasi-Spherical Cell Size Measurement Based on Lensless Imaging System 442 234 Transactions on NanoBioscience (TNB)

Adaptive Parameter Model for Quasi-Spherical Cell Size Measurement Based on Lensless Imaging System

Author(s): Shuaijun Li, Zhengpeng Li, Ningmei Yu, LI Dai, Jianwei Li

Many biological cells appear quasi-spherical, such as red blood cells, white blood cells, egg cells, cancer cells, etc. Cell size is an important basis for medical diagnosis. The traditional method…

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