Transactions on
NanoBioscience

The IEEE Transactions on NanoBioscience publishes basic and applied papers dealing both with engineering, physics, chemistry, modeling and computer science and with biology and medicine with respect to molecules, cells, tissues. The content of acceptable papers ranges from practical/clinical/environmental applications to formalized mathematical theory.
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Dan V. Nicolau
Editor-in-chief
Editor-in-chief

Dan has degrees in Chemical Engineering (PhD, MEng) and in Statistics, Cybernetics & Information Technology (MSc). His research covers biocomputation and biosimulation, nanodevices powered by protein molecular motors, surface science and engineering, micro- and nano-fabrication for semiconductor and biomedical devices, process modelling and control, and protein adsorption. Dan is a Professor of Bioengineering with McGill University, the Maria Zelenka-Roy Chair in Bioengineering, and the founding Chair of McGill’s Department of Bioengineering in the Faculty of Engineering. Dan authored more than 200 peer-reviewed publications, co-edited a book, and chaired more than 30 international conferences. He has been the Editor-in-Chief of the IEEE Transactions on NanoBioscience since January 1, 2020.

Email: dan.nicolau@mcgill.ca

Dan has degrees in Chemical Engineering (PhD, MEng) and in Statistics, Cybernetics & Information Technology (MSc). His research covers biocomputation and biosimulation, nanodevices powered by protein molecular motors, surface science and engineering, micro- and nano-fabrication for semiconductor and biomedical devices, process modelling and control, and protein adsorption. Dan is a Professor of Bioengineering with McGill University, the Maria Zelenka-Roy Chair in Bioengineering, and the founding Chair of McGill’s Department of Bioengineering in the Faculty of Engineering. Dan authored more than 200 peer-reviewed publications, co-edited a book, and chaired more than 30 international conferences. He has been the Editor-in-Chief of the IEEE Transactions on NanoBioscience since January 1, 2020.

Email: dan.nicolau@mcgill.ca

Quantum Speedup and Mathematical Solutions from Implementing Bio-molecular Solutions for the Independent Set Problem on IBM’s Quantum Computers

In this paper, we propose a bio-molecular algorithm with O(n2 + m) biological operations, O(2n) DNA strands, O(n) tubes and the longest DNA strand, O(n), for solving the independent-set problem for any graph G with m edges and n vertices. Next, we show that a new kind of the straightforward Boolean circuit yielded from the bio-molecular solutions with m NAND gates, (m + n × (n +1)) AND gates and ((n × (n + 1)) / 2) NOT gates can find the maximal independent-set(s) to the independent-set problem for any graph G with m edges and n vertices. We show that a new kind of the proposed quantum-molecular algorithm can find the maximal independent set(s) with the lower bound O(2n/2) queries and the upper bound Ω(2n/2) queries. This work offers an obvious evidence that to solve the independent-set problem in... Read more

In this paper, we propose a bio-molecular algorithm with O(n2 + m) biological operations, O(2n) DNA strands, O(n) tubes and the longest DNA strand, O(n), for solving the independent-set problem for any graph G with m edges and n vertices. Next, we show that a new kind of the straightforward Boolean circuit yielded from the bio-molecular solutions with m NAND gates, (m + n × (n +1)) AND gates and ((n × (n + 1)) / 2) NOT gates can find the maximal independent-set(s) to the independent-set problem for any graph G with m edges and n vertices. We show that a new kind of the proposed quantum-molecular algorithm can find the maximal independent set(s) with the lower bound O(2n/2) queries and the upper bound Ω(2n/2) queries. This work offers an obvious evidence that to solve the independent-set problem in any graph G with m edges and n vertices, bio-molecular computers are able to generate a new kind of the straightforward Boolean circuit such that by means of implementing it quantum computers can give a quadratic speed-up. This work also offers one obvious evidence that quantum computers can significantly accelerate the speed and enhance the scalability of bio-molecular computers. Furthermore, to justify the feasibility of the proposed quantum-molecular algorithm, we successfully solve a typical independent set problem for a graph G with three vertices and two edges by carrying out experiments on the backend ibmqx4 with five quantum bits and the backend simulator with 32 quantum bits on IBM’s quantum computer.

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Dr. Uche Chude-Okonkwo
IEEE TNB top reviewer for 2020
IEEE TNB top reviewer for 2020

Updates

Transactions on

NanoBioscience

April 2021
VOLUME 20
NUMBER 2
ITMCEL
20
The IEEE Transactions on NanoBioscience Volume 20 Issue 2 has been published.
Modeling of Anti-cancer Drug Release Kinetics from Liposomes and Micelles: A review
Nanocarriers, such as liposomes and micelles, were developed to enhance the delivery of therapeutic drugs to malignant tissues. Internal or external stimuli can be applied to achieve spatiotemporal controlled release from these carriers. This will result in enhancing their therapeutic... Read more
Targeted Drug Delivery for Cardiovascular Disease: Modeling of Modulated Extracellular Vesicle Release Rates
Invasive and medical therapy has led to major improvements in cardiovascular disease management, but important challenges remain open. The discovery of a nano-sized system of extracellular vesicles (EVs) is opening new possibilities for reprogramming malfunctioning cells and indicates that EVs... Read more
Articles
Silicon Carbide Nanoparticles based Nanofibrous Membrane in Comparison with Thin-Film Enzymatic Glucose Sensor
This work presents, silicon carbide nanoparticles (SiCNPs) embedded in a conductive polymer (CP) to be electrospun to fabricate a nanofibrous membrane and a thin-film. Electrochemical enzymatic glucose sensing mechanism of an electrospun nanofibrous membrane (ENFM) of SiCNPs in a CP... Read more
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Hierarchical micro-/nanotopography for tuning structures and mechanics of cells probed by atomic force microscopy
Extracellular matrix plays an important role in regulating the behaviors of cells, and utilizing matrix physics to control cell fate has been a promising way for cell and tissue engineering. However, the nanoscale situations taking place during the topography-regulated cell-matrix... Read more
Articles
Detection of blood glucose with hemoglobin content using compact photonic crystal fiber
We have proposed Twin Elliptical Core Photonic Crystal Fiber (TEC-PCF) sensor for the detection of blood glucose level under the influence of hemoglobin components. The main featuring of the proposed biosensor is to detect the wide range of blood glucose... Read more