Sequential analysis

HapIso: An Accurate Method for the Haplotype- Specific Isoforms Reconstruction From Long Single-Molecule Reads

Author(s): Serghei Mangul, Taegyun Harry Yang, Farhad Hormozdiari, Alexandra Marie Dainis, Elizabeth Tseng, Euan A. Ashley, Alex Zelikovsky, Eleazar Eskin
HapIso: An Accurate Method for the Haplotype- Specific Isoforms Reconstruction From Long Single-Molecule Reads 215 235 Transactions on NanoBioscience (TNB)

Sequencing of RNA provides the possibility to study an individual’s transcriptome landscape and determine allelic expression ratios. Single-molecule protocols generate multi-kilobase reads longer than most transcripts, allowing sequencing of complete…

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An Effective Approach for Glycan Structure De Novo Sequencing From HCD Spectra

Author(s): Weiping Sun, Miljan Kuljanin, Paula Pittock, Bin Ma, Kaizhong Zhang, Gilles A. Lajoie
An Effective Approach for Glycan Structure De Novo Sequencing From HCD Spectra 556 235 Transactions on NanoBioscience (TNB)

Mass spectrometry has become a widely used analytical technique for proteomics study because of its high throughput and sensitivity. Among those applications, a specific one is to characterize glycan structure.…

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