Gastric Contraction Imaging System Using a Three-Dimensional Endoscope
This paper presents a gastric contraction imaging system for assessment of gastric motility using a three-dimensional endoscope. Gastrointestinal diseases are mainly based on morphological abnormalities. However, gastrointestinal symptoms are sometimes apparent without visible abnormalities. One of the major factors for these diseases is abnormal gastrointestinal motility. For assessment of gastric motility, a gastric motility imaging system is needed.
Method: To assess the dynamic motility of the stomach, the proposed system measures three-dimensional gastric contractions derived from a three-dimensional profile of the stomach wall obtained with a developed three-dimensional endoscope. After obtaining contraction waves, their frequency, amplitude, and speed of propagation can be calculated using a Gaussian function.
Results: The proposed system was evaluated for three-dimensional measurements of several objects with known geometries. The results showed that the surface profiles could be obtained with an error of less than 10 percent of the distance between two different points on images. Subsequently, we evaluated the validity of a prototype system using a wave simulated model. In the experiment, the amplitude and position of waves could be measured with 1-mm accuracy.
Conclusions: The present results suggest that the proposed system can measure the speed and amplitude of contractions.
Clinical Impact: This system has low invasiveness and can assess the motility of the stomach wall directly in a three-dimensional manner. Our method can be used for examination of gastric morphological and functional abnormalities.
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See complete bios of the authors in the full version of this article.
Ms. Yoshimoto has B.E. and M.E. degrees in mechanical engineering from Osaka University, Osaka Japan in 2009 and 2011, respectively. She is currently pursuing a Ph.D. at the Graduate School of Medicine, Osaka University. Her current research interests include medical engineering and nursing engineering.
Dr. Yamada is a Professor at the Graduate School of Medicine of Osaka University since 2012. His research interests are optical information processing, Medical Engineering, 3D measurement, micromachining, and other fields. He is now engaged in research on nursing engineering. He is a member of IEEE, JSMBE, SICE, SPIE, and other societies.
Dr. Watabe is an Assistant Professor at Osaka University Graduate School of Medicine, Osaka, Japan. He was a postdoctoral fellow in Osaka University Graduate School of Frontier Biosciences from 2002 to 2004. His research interests include the field of gastroenterology, especially gastroenterological diseases and interstitial cells of Cajal.
Dr. Takeda completed the doctoral program at Osaka University (Graduate School of Medicine) in 2013. She became a project researcher at Osaka University in 2013. Her research interests are cancer, medical engineering, nursing engineering and other fields.
Dr. Nishimura is a postdoctal Researcher at Osaka University. He received his BS degree in applied physics, his MS and PhD degrees in information science from Osaka University in 2008, 2010, and 2013, respectively. His current research interests include information photonics and biomedical engineering.
Ms. Kido has been an assistant professor at the Graduate School of Medicine of Osaka University since 2013. She previously worked as a nurse and chief nurse of the National Hospital Organization. Her research topic is clinical nursing study. She is now engaged in research on nursing health assessment and nursing management.
Dr. Nagakura has been a professor at Osaka Electro-Communication University since 2002. His research interests are Medical Engineering, MEMS, Endoscope, 3D measurement, Image Processing, Medical Informatics, and Medical Design. He is a member of IEEE, JSMBE, JAMI, JSCAS, JSSD, and other societies.
Dr. Takahashi is a faculty member at Osaka City University, and since 2011, has been a Professor in the Dept. of Electric and Information Engineering. His current research interests include interactive 3D display, retinal projection display, wearable computers, and medical engineering. He is a member of SPIE and OSA.
Dr. Nishida has worked at Osaka University Hospital as a gastroenterologist at Osaka University Hospital since 2006. His research interests include gastrointestinal oncology and endoscopy. Dr. Nishida is also an Assistant Professor of Gastroenterology and Hepatology at Osaka University Graduated School of Medicine.
Dr. Iijima is an Assistant Professor at Osaka University Graduate School of Medicine, Osaka, Japan. He was a postdoctoral fellow in gastroenterology at Brigham and Women’s Hospital, Harvard Medical School from 2000 to 2002. His research interests include the field of gastroenterology, especially inflammatory bowel disease and mucosal immunology.
Dr. Tsujii is an Associate Professor at Osaka University Graduate School of Medicine, Osaka, Japan. He was a postdoctoral fellow in the division of Cell Biology, Vanderbilt University (Nashville, TN, USA) from 1993 to 1995. His research interests include gastroenterology, especially oncology and immunology in gastrointestinal cancer and inflammatory bowel disease.
Dr. Takehara is a Professor at Osaka University Graduate School of Medicine, Osaka, Japan. He was a Research Fellow at the Massachusetts General Hospital GI Unit (Boston, MA, USA). His research interests include cell death, innate immunity, viral hepatitis, and hepatocellular carcinoma.
Dr. Ohno served as a Senior Researcher at the Tokyo Metropolitan Institute for Neuroscience, and has been a Professor at Osaka University Graduate School of Medicine, Osaka, Japan since 1995. Her research interests include mathematical health science, operation metrics, robotics & design for innovative healthcare, and phenomenal design.