Drugs

A strategy for the in-silico assessment of drug eluting stents: A comparative study for the evaluation of Retinoic Acid as a novel drug candidate for drug eluting stents

A strategy for the in-silico assessment of drug eluting stents: A comparative study for the evaluation of Retinoic Acid as a novel drug candidate for drug eluting stents 150 150 IEEE Open Journal of Engineering in Medicine and Biology (OJEMB)
In this work, a methodology for the in-silico evaluation of drug eluting stents (DES) is presented. A stent model developed by Rontis S.A. has been employed. For modeling purposes two… read more

BeatProfiler: Multimodal In Vitro Analysis of Cardiac Function Enables Machine Learning Classification of Diseases and Drugs

BeatProfiler: Multimodal In Vitro Analysis of Cardiac Function Enables Machine Learning Classification of Diseases and Drugs 150 150 IEEE Open Journal of Engineering in Medicine and Biology (OJEMB)
Goal: Contractile response and calcium handling are central to understanding cardiac function and physiology, yet existing methods of analysis to quantify these metrics are often time-consuming, prone to mistakes, or… read more

Temozolomide in Combination With NF-κB Inhibitor Significantly Disrupts the Glioblastoma Multiforme Spheroid Formation

Author(s)3: Naze G. Avci, Nitin Tandon, Yasemin M. Akay, Yoshua Esquenazi, Hui Xia, Jay-Jiguang Zhu, Metin Akay, Lisa H. Schmitt
Temozolomide in Combination With NF-κB Inhibitor Significantly Disrupts the Glioblastoma Multiforme Spheroid Formation 742 558 IEEE Open Journal of Engineering in Medicine and Biology (OJEMB)

Glioblastoma multiforme (GBM) is the most common malignant primary brain tumor, accounting for 50% of all cases. GBM patients have a five-year survival rate of merely 5.6% and a median…

read more