Parkinson’s disease

An OpenSim-Based Closed-Loop Biomechanical Wrist Model for Subject-Specific Pathological Tremor Simulation

An OpenSim-Based Closed-Loop Biomechanical Wrist Model for Subject-Specific Pathological Tremor Simulation 150 150 Transactions on Neural Systems and Rehabilitation Engineering (TNSRE)
Objective: A pathological tremor (PT) is an involuntary rhythmic movement of varying frequency and amplitude that affects voluntary motion, thus compromising individuals’ independence. A comprehensive model incorporating PT’s physiological and… read more

Prediction of Freezing of Gait in Parkinson’s Disease Using Statistical Inference and Lower–Limb Acceleration Data

Author(s)3: Nader Naghavi, Eric Wade
Prediction of Freezing of Gait in Parkinson’s Disease Using Statistical Inference and Lower–Limb Acceleration Data 1024 371 Transactions on Neural Systems and Rehabilitation Engineering (TNSRE)

The freezing of gait (FoG) is a common type of motor dysfunction in advanced Parkinson’s disease (PD) associated with falls. Over the last decade, a significant amount of studies has…

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Optimal Control Perspective on Parkinson’s Disease: Increased Delay Between State Estimator and Controller Produces Tremor

Author(s)3: Christopher R. Kelley, Jeffrey L. Kauffman
Optimal Control Perspective on Parkinson’s Disease: Increased Delay Between State Estimator and Controller Produces Tremor 770 1000 Transactions on Neural Systems and Rehabilitation Engineering (TNSRE)
Parkinson’s disease produces tremor in a large subset of patients despite generally inhibiting movement. The pathophysiology of parkinsonian tremor is unclear, leading to uncertainty in how and why treatments reduce tremor with varying effectiveness. Models for parkinsonian tremor attempt to explain the underlying principles of tremor generation in the central nervous system, often focusing on neural activity of specific substructures. read more
Neurofeedback Control in Parkinsonian Patients Using Electrocorticography Signals Accessed Wirelessly With a Chronic, Fully Implanted Device

Neurofeedback Control in Parkinsonian Patients Using Electrocorticography Signals Accessed Wirelessly With a Chronic, Fully Implanted Device

Author(s)3: Preeya Khanna, Nicole C. Swann, Coralie de Hemptinne, Svjetlana Miocinovic, Andrew Miller, Philip A. Starr, Jose M. Carmena
Neurofeedback Control in Parkinsonian Patients Using Electrocorticography Signals Accessed Wirelessly With a Chronic, Fully Implanted Device 638 477 Transactions on Neural Systems and Rehabilitation Engineering (TNSRE)

       Parkinson’s disease (PD) is characterized by motor symptoms such as rigidity and bradykinesia that prevent normal movement. Beta band oscillations (13-30 Hz) in neural local field potentials (LFPs) have…

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