Interictal epileptiform spike (referred to as spike) detected from electroencephalograms lasting only 20- to 200-ms can provide a reliable evidence-based indicator for clinical seizure type diagnosis. Recent feature representation approaches focus either on the concrete-level or on abstract-level information mining of the spike, thus demonstrating suboptimal detection performance. Additionally, existing abstract-level information mining methods of the spike based deep learning networks have not realized the effective feature representation of long-term dependent distinguished information within similar waveform cycles caused by morphological heterogeneity, which affects detection performance. Thus, a multilevel feature learning method for accurate spike detection was proposed in this study. Specifically, the spatio-temporal-frequency multidomain information in concrete-level first are inferred the common mimetic properties of the spike using the multidomain feature extractors. Then, the effective feature representation of long-term dependent distinguished information within similar waveform cycles caused by morphological heterogeneity is suitably captured using the temporal convolutional network. Finally, the spatio-temporal-frequency multidomain long-term dependent feature representation of spike is calculated using the element-wise manner to fuse the feature representation in concrete- and abstract-levels. The experimental results indicate that the proposed method can achieve an accuracy of 90.62±1.38%, sensitivity of 90.38±1.52%, specificity of 91.00±1.60%, precision of 90.33±4.71%, and the false detection rate per minute is 0.148±0.020m-1, which are higher than when using the feature representation in the concrete- or abstract-level alone. Additionally, the detection results indicate that the proposed method avoids the subjectivity and inefficiency of visual inspection, and it enables a highly accurate detection of the spike.
Multilevel Feature Learning Method for Accurate Interictal Epileptiform Spike Detection https://www.embs.org/tnsre/wp-content/themes/movedo/images/empty/thumbnail.jpg 150 150 Transactions on Neural Systems and Rehabilitation Engineering (TNSRE) //www.embs.org/tnsre/wp-content/uploads/sites/15/2022/06/ieee-tnsre-logo2x.png
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