Tumors

Transport of Liposome Encapsulated Drugs in Voxelized Computational Model of Human Brain Tumors

Author(s): Ajay Bhandari, Ankit Bansal, Anup Singh, Niraj Sinha
Transport of Liposome Encapsulated Drugs in Voxelized Computational Model of Human Brain Tumors 215 215 Transactions on NanoBioscience (TNB)

There are many obstacles in the transport of chemotherapeutic drugs to tumor cells that lead to irregular and non-uniform uptake of drugs inside tumors. The study of these transport problems…

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Robust and Efficient Biomolecular Clustering of Tumor Based on p -Norm Singular Value Decomposition

Author(s): Xiang-Zhen Kong, Jin-Xing Liu, Chun-Hou Zheng, Mi-Xiao Hou, Juan Wang
Robust and Efficient Biomolecular Clustering of Tumor Based on p -Norm Singular Value Decomposition 215 235 Transactions on NanoBioscience (TNB)

High dimensionality has become a typical feature of biomolecular data. In this paper, a novel dimension reduction method named p-norm singular value decomposition (PSVD) is proposed to seek the low-rank…

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Modeling Contrast-Imaging-Assisted Optimal Targeted Drug Delivery: A Touchable Communication Channel Estimation and Waveform Design Perspective

Author(s): Yifan Chen, Yu Zhou, Ross Murch, Panagiotis Kosmas
Modeling Contrast-Imaging-Assisted Optimal Targeted Drug Delivery: A Touchable Communication Channel Estimation and Waveform Design Perspective 780 435 Transactions on NanoBioscience (TNB)

To maximize the effect of treatment and minimize the adverse effect on patients, we propose to optimize nanorobots-assisted targeted drug delivery (TDD) for locoregional treatment of tumor from the perspective…

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Use of Model Predictive Control and Artificial Neural Networks to Optimize the Ultrasonic Release of a Model Drug From Liposomes

Author(s): Hesham G. Moussa, Ghaleb A. Husseini, Nabil Abel-Jabbar, Salma E. Ahmad
Use of Model Predictive Control and Artificial Neural Networks to Optimize the Ultrasonic Release of a Model Drug From Liposomes 200 235 Transactions on NanoBioscience (TNB)

The use of echogenic liposomes to deliver chemotherapeutic agents for cancer treatment has gained wide recognition in the last 20 years. Cancerous cells can develop multiple drug resistance (MDR), in…

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OVarCall: Bayesian Mutation Calling Method Utilizing Overlapping Paired-End Reads

Author(s): Takuya Moriyama, Yuichi Shiraishi, Kenichi Chiba, Rui Yamaguchi, Seiya Imoto, Satoru Miyano
OVarCall: Bayesian Mutation Calling Method Utilizing Overlapping Paired-End Reads 215 235 Transactions on NanoBioscience (TNB)

Detection of somatic mutations from tumor and matched normal sequencing data has become a standard approach in cancer research. Although a number of mutation callers have been developed, it is…

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Molecular Communication Model for Targeted Drug Delivery in Multiple Disease Sites With Diversely Expressed Enzymes

Author(s): Uche A. K. Chude-Okonkwo, Reza Malekian, B. T. Sunil Maharaj
Molecular Communication Model for Targeted Drug Delivery in Multiple Disease Sites With Diversely Expressed Enzymes 556 235 Transactions on NanoBioscience (TNB)

Targeted drug delivery (TDD) for disease therapy using liposomes as nanocarriers has received extensive attention in the literature. The liposome’s ability to incorporate capabilities such as long circulation, stimuli responsiveness,…

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Centrifugal Filter Device for Detection of Rare Cells With Immuno-Binding

Author(s): Chih-Chung Chen, Yu-An Chen, Da-Jeng Yao
Centrifugal Filter Device for Detection of Rare Cells With Immuno-Binding 256 300 Transactions on NanoBioscience (TNB)

Many investigations have shown circulating tumor cells (CTCs) to serve as a significant biomarker of cancer progression and for cancer treatment. Multiple blood samples detection of CTCs during a course…

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3D silicon microstructures: a new tool for evaluating biological aggressiveness of tumour cells

Author(s): Sabina Merlo, Giuliano Mazzini, Francesca Carpignano, Salvatore Surdo, Francesca Aredia, Martina Torchio, Eugenio Erba, Marco Danova, Anna Scovassi, Giuseppe Barillaro
3D silicon microstructures: a new tool for evaluating biological aggressiveness of tumour cells 556 235 Transactions on NanoBioscience (TNB)

In this work, silicon micromachined structures (SMS), consisting of arrays of 3-µm-thick silicon walls separated by 50-µm-deep, 5-µm-wide gaps, were applied to investigate the behaviour of eight tumour cell lines,…

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