RNA

HapIso: An Accurate Method for the Haplotype- Specific Isoforms Reconstruction From Long Single-Molecule Reads

Author(s): Serghei Mangul, Taegyun Harry Yang, Farhad Hormozdiari, Alexandra Marie Dainis, Elizabeth Tseng, Euan A. Ashley, Alex Zelikovsky, Eleazar Eskin
HapIso: An Accurate Method for the Haplotype- Specific Isoforms Reconstruction From Long Single-Molecule Reads 215 235 Transactions on NanoBioscience (TNB)

Sequencing of RNA provides the possibility to study an individual’s transcriptome landscape and determine allelic expression ratios. Single-molecule protocols generate multi-kilobase reads longer than most transcripts, allowing sequencing of complete…

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Nanoparticles for siRNA-Based Gene Silencing in Tumor Therapy

Author(s): Anish Babu, Ranganayaki Muralidharan, Narsireddy Amreddy, Meghna Mehta, Anupama Munshi, Rajagopal Ramesh
Nanoparticles for siRNA-Based Gene Silencing in Tumor Therapy 780 435 Transactions on NanoBioscience (TNB)

Gene silencing through RNA interference (RNAi) has emerged as a potential strategy in manipulating cancer causing genes by complementary base-pairing mechanism. Small interfering RNA (siRNA) is an important RNAi tool…

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TargetM6A: Identifying N6-Methyladenosine Sites From RNA Sequences via Position-Specific Nucleotide Propensities and a Support Vector Machine

Author(s): Guang-Qing Li, Zi Liu, Hong-Bin Shen, Dong-Jun Yu
TargetM6A: Identifying N6-Methyladenosine Sites From RNA Sequences via Position-Specific Nucleotide Propensities and a Support Vector Machine 215 220 Transactions on NanoBioscience (TNB)

As one of the most ubiquitous post-transcriptional modifications of RNA, N6-methyladenosine ( m 6 A  ) plays an essential role in many vital biological processes. The identification of m 6 A  sites in RNAs…

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Heterogeneous Network Model to Infer Human Disease-Long Intergenic Non-Coding RNA Associations

Author(s): Gamage Upeksha Ganegoda, Min Li, Weiping Wang, Qilong Feng
Heterogeneous Network Model to Infer Human Disease-Long Intergenic Non-Coding RNA Associations 556 235 Transactions on NanoBioscience (TNB)

ACCESS PAPER DATA READ FULL ARTICLE ON IEEE XPLORE Abstract With the knowledge of molecular biology it is highlighting that long non-coding RNAs (lncRNAs) play a critical role in many…

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