Proteins

A High-Throughput Microdroplet-Based Single Cell Transfection Method for Gene Knockout Based on the CRISPR/Cas9 System

A High-Throughput Microdroplet-Based Single Cell Transfection Method for Gene Knockout Based on the CRISPR/Cas9 System 150 150 Transactions on NanoBioscience (TNB)
The efficient application of the newly developed gene-editing method CRISPR/Cas9 requires more accurate intracellular gene delivery. Traditional delivery approaches, such as lipotransfection and non-viral delivery methods, must contend with major… read more

COTiR: Molecular Communication Model for Synthetic Exosome-Based Tissue Regeneration

COTiR: Molecular Communication Model for Synthetic Exosome-Based Tissue Regeneration 150 150 Transactions on NanoBioscience (TNB)
Mesenchymal stem cell (MSC)-derived exosomes are recognized as an unparalleled therapy for tissue damage rendered by COVID-19 infection and subsequent hyper-inflammatory immune response. However, the natural targeting mechanism of exosomes… read more

Size-Dependent Protein Adsorption on a Nanoparticle

Size-Dependent Protein Adsorption on a Nanoparticle 150 150 Transactions on NanoBioscience (TNB)
This study presents the mechanism of adsorption of a model protein within an electrical double layer (EDL) of a charged silica NP in an aqueous salt medium. In contrast to… read more