Couplings

HapIso: An Accurate Method for the Haplotype- Specific Isoforms Reconstruction From Long Single-Molecule Reads

Author(s): Serghei Mangul, Taegyun Harry Yang, Farhad Hormozdiari, Alexandra Marie Dainis, Elizabeth Tseng, Euan A. Ashley, Alex Zelikovsky, Eleazar Eskin
HapIso: An Accurate Method for the Haplotype- Specific Isoforms Reconstruction From Long Single-Molecule Reads 215 235 Transactions on NanoBioscience (TNB)

Sequencing of RNA provides the possibility to study an individual’s transcriptome landscape and determine allelic expression ratios. Single-molecule protocols generate multi-kilobase reads longer than most transcripts, allowing sequencing of complete…

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Integrating Omics Data With a Multiplex Network-Based Approach for the Identification of Cancer Subtypes

Author(s): Haiying Wang, Huiru Zheng, Jianxin Wang, Chaoyang Wang, Fang-Xiang Wu
Integrating Omics Data With a Multiplex Network-Based Approach for the Identification of Cancer Subtypes 556 235 Transactions on NanoBioscience (TNB)

Comprehensive characterization and identification of cancer subtypes have a number of applications and implications in life science and cancer research. Technologies centered on the integration of omics data hold great…

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