cancer

Robust and Efficient Biomolecular Clustering of Tumor Based on p -Norm Singular Value Decomposition

Author(s): Xiang-Zhen Kong, Jin-Xing Liu, Chun-Hou Zheng, Mi-Xiao Hou, Juan Wang
Robust and Efficient Biomolecular Clustering of Tumor Based on p -Norm Singular Value Decomposition 215 235 Transactions on NanoBioscience (TNB)

High dimensionality has become a typical feature of biomolecular data. In this paper, a novel dimension reduction method named p-norm singular value decomposition (PSVD) is proposed to seek the low-rank…

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Detection of Glutathione by Glutathione-S-Transferase – Nanoconjugate Ensemble Electrochemical Device

Author(s): Ujjwol Barman, Gargi Mukhopadhyay, Namami Goswami, Siddhartha S. Ghosh, Roy P. Palathinkal
Detection of Glutathione by Glutathione-S-Transferase – Nanoconjugate Ensemble Electrochemical Device 215 205 Transactions on NanoBioscience (TNB)

This paper reports a novel electrochemical method for detection of Glutathione (GSH) using Glutathione-S-Transferase (GST) – ZnO composite nanoparticles to investigate the prospects of the method for detection of cancer…

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Abnormality Detection in Correlated Gaussian Molecular Nano-Networks: Design and Analysis

Author(s): Farshad Lahouti, Siavash Ghavami
Abnormality Detection in Correlated Gaussian Molecular Nano-Networks: Design and Analysis 200 235 Transactions on NanoBioscience (TNB)

A nano-abnormality detection scheme (NADS) in molecular nano-networks is studied. This is motivated by the fact that early detection of diseases such as cancer plays a crucial role in their…

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Use of Model Predictive Control and Artificial Neural Networks to Optimize the Ultrasonic Release of a Model Drug From Liposomes

Author(s): Hesham G. Moussa, Ghaleb A. Husseini, Nabil Abel-Jabbar, Salma E. Ahmad
Use of Model Predictive Control and Artificial Neural Networks to Optimize the Ultrasonic Release of a Model Drug From Liposomes 200 235 Transactions on NanoBioscience (TNB)

The use of echogenic liposomes to deliver chemotherapeutic agents for cancer treatment has gained wide recognition in the last 20 years. Cancerous cells can develop multiple drug resistance (MDR), in…

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Nanoparticles for siRNA-Based Gene Silencing in Tumor Therapy

Author(s): Anish Babu, Ranganayaki Muralidharan, Narsireddy Amreddy, Meghna Mehta, Anupama Munshi, Rajagopal Ramesh
Nanoparticles for siRNA-Based Gene Silencing in Tumor Therapy 780 435 Transactions on NanoBioscience (TNB)

Gene silencing through RNA interference (RNAi) has emerged as a potential strategy in manipulating cancer causing genes by complementary base-pairing mechanism. Small interfering RNA (siRNA) is an important RNAi tool…

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Block-Constraint Robust Principal Component Analysis and its Application to Integrated Analysis of TCGA Data

Author(s): Jin-Xing Liu, Ying-Lian Gao, Chun-Hou Zheng, Yong Xu, Jiguo Yu
Block-Constraint Robust Principal Component Analysis and its Application to Integrated Analysis of TCGA Data 215 259 Transactions on NanoBioscience (TNB)

The Cancer Genome Atlas (TCGA) dataset provides us more opportunities to systematically and comprehensively learn some biological mechanism of cancers formation, growth and metastasis. Since TCGA dataset includes heterogeneous data,…

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Identifying Individual-Cancer-Related Genes by Re-balancing the Training Samples

Author(s): Bolin Chen, Xuequn Shang, Min Li, Jianxin Wang, Fang-Xiang Wu
Identifying Individual-Cancer-Related Genes by Re-balancing the Training Samples 556 235 Transactions on NanoBioscience (TNB)

The identification of individual-cancer-related genes typically is an imbalanced classification issue. The number of known cancer-related genes is far less than the number of all unknown genes, which makes it…

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Integrating Omics Data With a Multiplex Network-Based Approach for the Identification of Cancer Subtypes

Author(s): Haiying Wang, Huiru Zheng, Jianxin Wang, Chaoyang Wang, Fang-Xiang Wu
Integrating Omics Data With a Multiplex Network-Based Approach for the Identification of Cancer Subtypes 556 235 Transactions on NanoBioscience (TNB)

Comprehensive characterization and identification of cancer subtypes have a number of applications and implications in life science and cancer research. Technologies centered on the integration of omics data hold great…

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Molecular Communication Model for Targeted Drug Delivery in Multiple Disease Sites With Diversely Expressed Enzymes

Author(s): Uche A. K. Chude-Okonkwo, Reza Malekian, B. T. Sunil Maharaj
Molecular Communication Model for Targeted Drug Delivery in Multiple Disease Sites With Diversely Expressed Enzymes 556 235 Transactions on NanoBioscience (TNB)

Targeted drug delivery (TDD) for disease therapy using liposomes as nanocarriers has received extensive attention in the literature. The liposome’s ability to incorporate capabilities such as long circulation, stimuli responsiveness,…

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Centrifugal Filter Device for Detection of Rare Cells With Immuno-Binding

Author(s): Chih-Chung Chen, Yu-An Chen, Da-Jeng Yao
Centrifugal Filter Device for Detection of Rare Cells With Immuno-Binding 256 300 Transactions on NanoBioscience (TNB)

Many investigations have shown circulating tumor cells (CTCs) to serve as a significant biomarker of cancer progression and for cancer treatment. Multiple blood samples detection of CTCs during a course…

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