Microtubule Deformation Modulates Intracellular Transport by Kinesin Differently than Dynein

Microtubule Deformation Modulates Intracellular Transport by Kinesin Differently than Dynein 150 150 Transactions on NanoBioscience (TNB)

Abstract:

Mechanical stress on cells is transmitted through many biological processes, for example, cell shape control, tissue patterning, and axonal homeostasis. Microtubules, a cytoskeletal component, presumably play a significant role in the mechanoregulation of cellular processes. We investigate motor protein-driven transport of quantum dots along mechanically deformed microtubules. We found that …

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