Microfluidic-Assisted Fabrication of Flexible and Location Traceable Organo-Motor

Microfluidic-Assisted Fabrication of Flexible and Location Traceable Organo-Motor 556 235 Transactions on NanoBioscience (TNB)

In this paper, we fabricate a flexible and location traceable micro-motor, named organo-motor, assisted by microfluidic devices and with high throughput. The organo-motors are composed of organic hydrogel material, poly (ethylene glycol) diacrylate (PEGDA), which can provide the flexibility of their structure. For spatial and temporal traceability of the organo-motors under magnetic resonance imaging (MRI), superparamagnetic iron oxide nanoparticles (SPION; Fe3O4) were incorporated into the PEGDA microhydrogels. Furthermore, a thin layer of platinum (Pt) was deposited onto one side of the SPION-PEGDA microhydrogels providing geometrical asymmetry and catalytic propulsion in aqueous fluids containing hydrogen peroxide solution, H2O2. Furthermore, the motion of the organo-motor was controlled by small external magnet enabled by the presence of SPION in the motor architecture.