The IEEE transactions on nanobioscience thank its reviewers, editorial board members, and most importantly its authors and readers for their support in 2014 and look forward to serving them even better in 2015! The Transactions experienced a 50% growth in submissions relative to 2013 to almost 150 manuscripts. The average time to first decision for manuscripts submitted in 2014 was 1 month and the rejection rate was 60%. The impact factor returned to its long-term average of 1.8. The special issues on “The International Conference on Bioinformatics and Biomedicine” edited by Bin Hu, Xiaohua Hu and De-Shuang Huang (issue 2) and “Molecular Computing” edited by Tadashi Nakano and Athanasios Vasilakos (issue 3) were highlights of volume 13 of the Transactions on NanoBioscience. Furthermore, we launched our new website (tnb.embs.org) providing up-to-date information for authors and readers.