Yttrium-Iron Garnet Film Magnetometer for Registration of Magnetic Nano- and Submicron Particles: In Vitro and In Vivo Studieshttps://www.embs.org/tbme/wp-content/uploads/sites/19/2023/12/TBME-00169-2023-Website-Image-scaled.jpg25601648IEEE Transactions on Biomedical Engineering (TBME)IEEE Transactions on Biomedical Engineering (TBME)//www.embs.org/tbme/wp-content/uploads/sites/19/2022/06/ieee-tbme-logo2x.png
This article introduces an innovative room-temperature magnetometer, based on yttrium-iron garnet film and optical signal registration. The sensor demonstrates high sensitivity and is feasible for quantitative detection of magnetic nano- and submicron particles in biological fluids and tissues, as validated through successful in vitro and in vivo detection of remanent magnetization of magnetic nanoparticles.
Author(s)3: Yaser Hadadian, João H. Uliana, Antonio A. O. Carneiro, Theo Z. Pavan
A Novel Theranostic Platform: Integration of Magnetomotive and Thermal Ultrasound Imaging with Magnetic Hyperthermiahttps://www.embs.org/tbme/wp-content/uploads/sites/19/2020/12/TBME-01663-2019-Highlight-Image.gif170177IEEE Transactions on Biomedical Engineering (TBME)IEEE Transactions on Biomedical Engineering (TBME)//www.embs.org/tbme/wp-content/uploads/sites/19/2022/06/ieee-tbme-logo2x.png
This paper describes a theranostic system where a single coil is used to apply two different magnetic fields for magnetic hyperthermia (therapy) and magnetomotive ultrasound (diagnostics). This integrated system is proposed to address two of the main challenges that hinder magnetic hyperthermia to be translated into clinical routine: localizing the magnetic nanoparticles (magnetomotive ultrasound) and real-time temperature monitoring (ultrasound thermometry). We believe this study can open up a new horizon in magnetic hyperthermia, where planning, treating, and monitoring can be achieved through a single nanotheranostic agent and a cost-effective, portable, real-time and clinically available imaging device that uses non-ionizing radiation.
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