rigid body motion

Light-based, or biophotonic, technologies are safe and portable tools for assessing tissue health. Above, we see how a handheld optical probe uses frequency modulated light to assess subsurface tissue composition by measuring molecular concentrations of absorbing and scattering media. However, assessing large tissue regions (e.g., in breast cancer) is traditionally a tedious and rigid process with ramifications for longitudinal follow-up. Here, we developed an overhead camera system that, paired with probe geometry knowledge, can track the probe in 3D as it is scanned across the tissue (as above), enabling real-time operator driven optical imaging. read more