Real-time cavitation monitoring during optical coherence tomography guided photo-mediated ultrasound therapy of the retinahttps://www.embs.org/tbme/wp-content/uploads/sites/19/2024/07/TBME-01347-2023-Website-Image-R.gif710400IEEE Transactions on Biomedical Engineering (TBME)IEEE Transactions on Biomedical Engineering (TBME)//www.embs.org/tbme/wp-content/uploads/sites/19/2022/06/ieee-tbme-logo2x.png
Real-time monitoring of cavitation activity in microvessels by detecting signal washout phenomena during optical coherence tomography can improve safety when performing photo-mediated ultrasound therapy to remove retinal/choroidal microvessels.
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Acoustic Force Elastography Microscopyhttps://www.embs.org/tbme/wp-content/uploads/sites/19/2023/02/TBME-00801-2022-Website_Image.jpg789444IEEE Transactions on Biomedical Engineering (TBME)IEEE Transactions on Biomedical Engineering (TBME)//www.embs.org/tbme/wp-content/uploads/sites/19/2022/06/ieee-tbme-logo2x.png
Acoustic force elastography microscopy (AFEM) can be used to observe the spatial variation of mechanical properties of hydrogels in a non-contact manner and address the limitations of destructive mechanical testing measurements.
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Direct Visualization and Quantitative Imaging of Small Airway Anatomy In Vivo Using Deep Learning Assisted Diffractive OCThttps://www.embs.org/tbme/wp-content/uploads/sites/19/2022/12/TBME-00473-2022-Website-Image.jpg795411IEEE Transactions on Biomedical Engineering (TBME)IEEE Transactions on Biomedical Engineering (TBME)//www.embs.org/tbme/wp-content/uploads/sites/19/2022/06/ieee-tbme-logo2x.png
This is the first study to demonstrate direct visualization and automated quantification of 3D subsurface microstructures in small airways in vivo with a novel deep-learning assisted diffractive optical coherence tomography.
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Author(s)3: Abigail Joyce Deloria, Sandra Haider, Bianca Dietrich, Victoria Kunihs, Simon Oberhofer, Martin Knofler, Rainer A. Leitgeb, Mengyang Liu, Wolfgang Drexler, Richard Haindl
Ultra-high-resolution 3D optical coherence tomography reveals inner structures of human placenta-derived trophoblast organoidshttps://www.embs.org/tbme/wp-content/uploads/sites/19/2021/07/TMBE-01565-2020-Highlight-Image.gif170177IEEE Transactions on Biomedical Engineering (TBME)IEEE Transactions on Biomedical Engineering (TBME)//www.embs.org/tbme/wp-content/uploads/sites/19/2022/06/ieee-tbme-logo2x.png
Many pregnancy complications are assumed to have their pathophysiological roots in early stages of placentation. Hence, trophoblast research represents a pre-requisite to help preventing pregnancy disorders that endangers uncomplicated gestations and jeopardizes maternal/fetal wellbeing later in life. Recently established 3D trophoblast organoids (TB-ORG) advanced human placental research. However, gold standard methods for determining TB-ORG architectures lack imaging depth and/or are endpoint analyses. We addressed these problems with 3D optical coherence tomography (OCT). This work demonstrates for the first time that OCT resolves label-free inner structures of TB-ORG during cultivation and enables qualitative/quantitative assessment of their differentiation status without sample destruction.
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Author(s)3: Mark Draelos, Gao Tang, Brenton Keller, Anthony Kuo, Kris Hauser, Joseph A. Izatt
Optical Coherence Tomography Guided Robotic Needle Insertion for Deep Anterior Lamellar Keratoplastyhttps://www.embs.org/tbme/wp-content/uploads/sites/19/2020/06/TBME-01519-2019-Highlight-Image.gif170177IEEE Transactions on Biomedical Engineering (TBME)IEEE Transactions on Biomedical Engineering (TBME)//www.embs.org/tbme/wp-content/uploads/sites/19/2022/06/ieee-tbme-logo2x.png
Deep anterior lamellar keratoplasty (DALK) is a promising form of partial-thickness cornea transplantation, but its popular “big bubble” technique frequently fails due to difficulty controlling a needle insertion into the cornea. We addressed the surgeon challenges that reduce success rates by demonstrating an optical coherence tomography (OCT)-guided, robotically stabilized workstation for manually or automatically performing DALK needle insertions. In a study with cornea fellows, we found that OCT visualization versus the standard stereo microscope was a key enabler in manual attempts and that our automatic robotic method met or exceeded the performance of cornea fellows.
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Glaucoma progression detection using structural retinal nerve fiber layer measurements and functional visual field pointshttps://www.embs.org/tbme/wp-content/uploads/sites/19/2014/04/April-2014-Bowd.gif556235IEEE Transactions on Biomedical Engineering (TBME)IEEE Transactions on Biomedical Engineering (TBME)//www.embs.org/tbme/wp-content/uploads/sites/19/2022/06/ieee-tbme-logo2x.png
Siamak Yousefi, Michael H. Goldbaum, Madhusudhanan Balasubramanian, Tzyy-Ping Jung, Robert N. Weinreb, Felipe A. Medeiros, Linda M. Zangwill, Jeffrey M. Liebmann, Christopher A. Girkin, and Christopher Bowd University of California San…
