Experimental Investigation of Microfluidic Device for Platelet Activationhttps://www.embs.org/tbme/wp-content/uploads/sites/19/2023/02/TBME-02359-2021-Website_Image.jpg789444IEEE Transactions on Biomedical Engineering (TBME)IEEE Transactions on Biomedical Engineering (TBME)//www.embs.org/tbme/wp-content/uploads/sites/19/2022/06/ieee-tbme-logo2x.png
We have developed microfluidic devices to activate platelets by using shear-induced platelet activation approach. These biomedical devices can be used in Platelet-rich plasma treatments without any adverse immune reaction.
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Author(s)3: Michele D’Orazio, Riccardo Reale, Adele De Ninno, Maria A. Brighetti, Arianna Mencattini, Luca Businaro, Eugenio Martinelli, Paolo Bisegna, Alessandro Travaglini, Federica Caselli
Electro-optical classification of pollen grains via microfluidics and machine learninghttps://www.embs.org/tbme/wp-content/uploads/sites/19/2022/02/TBME-00843-2021-Highlight-Image_340x354-1.gif340354IEEE Transactions on Biomedical Engineering (TBME)IEEE Transactions on Biomedical Engineering (TBME)//www.embs.org/tbme/wp-content/uploads/sites/19/2022/06/ieee-tbme-logo2x.png
This interdisciplinary work involves sensor science, microfluidics, machine learning, and palynology. Palynology – i.e., the study of pollen and fungal spores – finds applications in high-impact fields like air quality control, allergology, and agriculture. Traditionally, the study of pollen takes place through microscopic analysis performed by specialized operators, after staining of the sample. The procedure requires long times and is prone to human errors. Therefore, there is an unmet need for accurate, label-free, and automated systems for the analysis of pollen, ideally within a field-portable and cost-effective platform. In this framework, we propose an original multimodal approach.
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Author(s)3: Vahid Farmehini, Walter Varhue, Armita Salahi, Alexandra R. Hyler, Jaka Čemažar, Rafael Davalos, Nathan S. Swami
On-Chip Impedance Quantification of Parasitic Voltages During AC Electrokinetic Trappinghttps://www.embs.org/tbme/wp-content/uploads/sites/19/2020/05/TBME-00582-2019-Highlight-Image.jpg170177IEEE Transactions on Biomedical Engineering (TBME)IEEE Transactions on Biomedical Engineering (TBME)//www.embs.org/tbme/wp-content/uploads/sites/19/2022/06/ieee-tbme-logo2x.png
Monitoring the effectiveness and location of cell or particle trapping under microfluidic force fields is currently achieved by cumbersome imaging methods that require extensive microscopy to be conducted by a trained operator, with limited ability to rapidly trigger downstream decisions. We present an embedded circuit for an impedance sensor that directly interfaces to a microfluidic chip for the monitoring of cell or particle trapping based on the level and frequency response of parasitic voltage drops measured during AC electrokinetic manipulation, to enable assessment of trapping efficacy of the device geometry and to rapidly inform downstream cell separation decisions.
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Author(s)3: Jing Liu, Anna R. Sternberg, Shabnam Ghiasvand, Yevgeny Berdichevsky
Epilepsy-on-a-chip System for Antiepileptic Drug Discoveryhttps://www.embs.org/tbme/wp-content/uploads/sites/19/2019/05/TBME-00507-2018-Highlight-Image.gif170177IEEE Transactions on Biomedical Engineering (TBME)IEEE Transactions on Biomedical Engineering (TBME)//www.embs.org/tbme/wp-content/uploads/sites/19/2022/06/ieee-tbme-logo2x.png
Development of antiepileptic drugs is currently complicated by the long time course of epileptogenesis. This process occurs on a time scale of weeks to months in animal models, and…
Author(s)3: Miguel E. Combariza, Xinghuo Yu, Warwick Nesbitt, Arnan Mitchell, Francisco J. Tovar-Lopez
Nonlinear Dynamic Modelling of Platelet Aggregation via Microfluidic Deviceshttps://www.embs.org/tbme/wp-content/uploads/sites/19/2015/06/July-1A.png216284IEEE Transactions on Biomedical Engineering (TBME)IEEE Transactions on Biomedical Engineering (TBME)//www.embs.org/tbme/wp-content/uploads/sites/19/2022/06/ieee-tbme-logo2x.png
Miguel E. Combariza, Xinghuo Yu, Warwick S. Nesbitt, Arnan Mitchell, and Francisco J. Tovar-Lopez, RMIT University, Australia, Volume 62, Issue 7, Page: 1718-1727 The development of blood clots at sites of atherosclerotic…
Toward Integrated Molecular Diagnostic System (iMDx): Principles and Applicationshttps://www.embs.org/tbme/wp-content/uploads/sites/19/2014/04/14-60th-Luke-Lee1.gif556235IEEE Transactions on Biomedical Engineering (TBME)IEEE Transactions on Biomedical Engineering (TBME)//www.embs.org/tbme/wp-content/uploads/sites/19/2022/06/ieee-tbme-logo2x.png
Seung-min Park, Andrew Sabour, Jun Ho Son, Sang Hun Lee, Luke Lee Stanford University & University of California, Berkeley, Volume 61, Issue 5, Page: 1506-1521 A new golden age in medicine will…
