Holographic acoustic manipulation

3D Acoustic Manipulation of Living Cells and Organisms Based on 2D Array

Author(s): Ye Yang, Teng Ma, Qi Zhang, Jiqing Huang, Yongchuan Li, Congzhi Wang, Hairong Zheng
3D Acoustic Manipulation of Living Cells and Organisms Based on 2D Array IEEE Transactions on Biomedical Engineering (TBME)
This work aims to realize programmable manipulation for living cells and micro-organisms in a common Petri dish by using holographic acoustic tweezers. Based on a self-developed 2D ultrasound matrix array, we successfully synthesize various complex acoustic fields and achieve the precise regulation of the fields both in space and time, and further build a holographic acoustic tweezer system compatible with microscopic imaging. This system innovatively realizes multidimensional translation, rotation, orientation, and levitation of living cells and micro-organisms, thereby demonstrating their value for advancing research in the fields of cell assembly, tissue engineering, and micro-robot driving. read more