3D Acoustic Manipulation of Living Cells and Organisms Based on 2D Array
IEEE Transactions on Biomedical Engineering (TBME)
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This work aims to realize programmable manipulation for living cells and micro-organisms in a common Petri dish by using holographic acoustic tweezers. Based on a self-developed 2D ultrasound matrix array, we successfully synthesize various complex acoustic fields and achieve the precise regulation of the fields both in space and time, and further build a holographic acoustic tweezer system compatible with microscopic imaging. This system innovatively realizes multidimensional translation, rotation, orientation, and levitation of living cells and micro-organisms, thereby demonstrating their value for advancing research in the fields of cell assembly, tissue engineering, and micro-robot driving.
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