Gene therapy

In-vivo Intrathecal Tracer Dispersion in Cynomolgus Monkey Validates Wide Biodistribution Along Neuraxis

Author(s)3: Ivan Nestorov, Ajay Verma, Jenna Sullivan, Andreas A. Linninger, Kevin Tangen, Robert W. Holt
In-vivo Intrathecal Tracer Dispersion in Cynomolgus Monkey Validates Wide Biodistribution Along Neuraxis 170 133 IEEE Transactions on Biomedical Engineering (TBME)

Intrathecal (IT) delivery is a drug administration method that bypasses the blood-brain barrier by injecting therapeutic molecules directly into the central nervous system. In vivo tracer infusion experiments performed in…

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