Cancer Therapies Archives - IEEE Transactions on Biomedical Engineering (TBME)

February 23, 2017

Multiscale Modeling of Glioblastoma Suggests that the Partial Disruption of Vessel/Cancer Stem Cell Crosstalk Can Promote Tumor Regression without Increasing Invasiveness

Author(s)3: Huaming Yan, Mónica Romero-López, Hermann B. Frieboes, Christopher C. W. Hughes, John S. Lowengrub

Multiscale Modeling of Glioblastoma Suggests that the Partial Disruption of Vessel/Cancer Stem Cell Crosstalk Can Promote Tumor Regression without Increasing Invasiveness https://www.embs.org/tbme/wp-content/uploads/sites/19/2017/02/Image170x177.gif 170 177 IEEE Transactions on Biomedical Engineering (TBME) IEEE Transactions on Biomedical Engineering (TBME) //www.embs.org/tbme/wp-content/uploads/sites/19/2022/06/ieee-tbme-logo2x.png February 23, 2017 March 4, 2022

In glioblastoma, the crosstalk between vascular endothelial cells (VECs) and glioma stem cells (GSCs) has been shown to enhance tumor growth. We develop a hybrid continuum-discrete mathematical model and show…