breast cancer

A breast-specific MR guided focused ultrasound platform and treatment protocol: first-in-human technical evaluation

Author(s): Allison Payne, Robb Merrill, Emilee Minalga, J. Rock Hadley, Henrik Odéen, Lorne W. Hofstetter, Sara Johnson, Christine Tunon de Lara, Sophie Auriol, Stephanié Recco, Erik Dumont, Dennis L. Parker, Jean Palussiere
A breast-specific MR guided focused ultrasound platform and treatment protocol: first-in-human technical evaluation 176 170 IEEE Transactions on Biomedical Engineering (TBME)
Breast cancer remains one of the most common cancers among women. The development of novel technology for minimally-invasive treatments will provide important new treatment options for many breast cancer patients. This work presents a breast-specific magnetic resonance (MR) guided focused ultrasound system for the treatment of localized breast tumors. The unique design of the system allows for high quality MR images for treatment planning and assessment, target accuracy determination with volumetric magnetic resonance-acoustic radiation force imaging, and real time treatment monitoring with magnetic resonance thermometry. Technical specification for the system are provided as well as preliminary results from a first-in-human clinical trial. read more

A multiscale agent-based model of ductal carcinoma in situ

Author(s): Joseph D. Butner, David Fuentes, Bulent Ozpolat, George A. Calin, Xiaobo Zhou, John S. Lowengrub, Vittorio Cristini, Zhihui Wang
A multiscale agent-based model of ductal carcinoma in situ 170 176 IEEE Transactions on Biomedical Engineering (TBME)
Breast cancer is the most frequently diagnosed cancer in the United States, and about 17% of these occur within the mammary gland duct, known as ductal carcinoma in situ (DCIS). We have developed a multiscale, lattice-free agent-based model of DCIS, incorporating both molecular and cellular scales, to study how phenotypic and signaling changes influence the key early stages of disease development. By simulating the effects of bidirectional feedback between these scales, we have gained valuable insights into how this complex interplay affects disease progression, and have identified key processes that may be optimal prognostic indicators of future disease advancement. read more

3D Microwave Tomography Using the Soft Prior Regularization Technique: Evaluation in Anatomically-Realistic MRI-Derived Numerical Breast Phantoms

Author(s): Amir H. Golnabi, Paul M. Meaney, Shireen D. Geimer, Keith D. Paulsen
3D Microwave Tomography Using the Soft Prior Regularization Technique: Evaluation in Anatomically-Realistic MRI-Derived Numerical Breast Phantoms 170 178 IEEE Transactions on Biomedical Engineering (TBME)

In this work, we present methods and results for fusion of magnetic resonance imaging(MRI) breast images with microwave tomography through a soft prior regularization technique. This method incorporates accurate boundary…

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Flexible Sixteen Antenna Array for Microwave Breast Cancer Detection

Author(s): Hadi Bahramiabarghouei, Emily Porter, Adam Santorelli, Benoit Gosselin, Milica Popović, Leslie A. Rusch
Flexible Sixteen Antenna Array for Microwave Breast Cancer Detection 170 177 IEEE Transactions on Biomedical Engineering (TBME)

H. Bahramiabarghouei, E. Porter, A. Santorelli, B. Gosselin, M. Popović, and L. A. Rusch, Laval University & McGill University, Volume 62, Issue 10, Page 2516-2525 Radar based microwave imaging (MWI) has…

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Breast Cancer Histopathology Image Analysis: A Review

Breast Cancer Histopathology Image Analysis: A Review 556 235 IEEE Transactions on Biomedical Engineering (TBME)

Mitko Veta, Josien P.W. Pluim, Paul J. van Diest, and Max A. Viergever University Medical Center Utrecht, Utrecht, The Netherlands, Volume 61, Issue 5, Page: 1400-1411 Pathology labs are currently…

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