Biomedical applications of radiation

Development and Characterization of a Non-Thermal Plasma Source for Therapeutic Treatments

Author(s)3: Rosendo Pena-Eguiluz, Jorge H. Serment-Guerrero, Erika P. Azorin-Vega, Antonio Mercado-Cabrera, Allan A. Flores-Fuentes, Bethsabet Jaramillo-Sierra, Alma N. Hernanez-Arias, Karina Giron-Romero, Regulo Lopez-Callejas, Benjamin G. Rodriguez-Mendez, Raul Valencia-Alvarado
Development and Characterization of a Non-Thermal Plasma Source for Therapeutic Treatments 170 177 IEEE Transactions on Biomedical Engineering (TBME)
A non−thermal plasma (NTP) system constituted by a radiofrequency generator directly coupled to a treatment probe is described. The NTP generated was analyzed and characterized to determine a plasma safety profile and a spreading technique to be used on heat−sensitive matter. When NTP interacts with surrounding air particles produces reactive oxygen and nitrogen species that exhibit bactericidal and antiseptic effects due to their strong biochemical reactivity. Afterward, the NTP source was validated through bacterial deactivation trials, biological tests and promoting and in vivo wound closure performed in mice. NTP source demonstrated faster wound healing than that performed with conventional treatments. read more