IEEE Transactions on
Biomedical Engineering

IEEE Transactions on Biomedical Engineering contains basic and applied papers dealing with biomedical engineering. Papers range from engineering development in methods and techniques with biomedical applications to experimental and clinical investigations with engineering contributions.
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Xiaochuan Pan
Editor-in-chief
Editor-in-chief

"Xiaochuan Pan is currently Professor of Radiology, Radiation & Cellular Oncology, Committee in Medical Physics, the College, and the University of Chicago Medicine Comprehensive Cancer Center at The University of Chicago. He received the BS (1982) and MS (1985) degrees in physics from Beijing University and the Institute of Physics, Science Academy of China and the MS (1988) and PhD (1991) degrees in physics from The University of Chicago. Following post-doc training in medical imaging from 1992-1994 in the Department of Radiology at The University of Chicago, he was appointed as an Assistant Professor of Radiology before being promoted to Associate Professor and Professor of Radiology in 2001 and 2006.

Professor Pan’s research centers on physics, algorithms, and engineering underpinning tomographic imaging and its biomedical and clinical applications. He and his laboratory have conducted research on advanced theory and algorithms for... Read more

"Xiaochuan Pan is currently Professor of Radiology, Radiation & Cellular Oncology, Committee in Medical Physics, the College, and the University of Chicago Medicine Comprehensive Cancer Center at The University of Chicago. He received the BS (1982) and MS (1985) degrees in physics from Beijing University and the Institute of Physics, Science Academy of China and the MS (1988) and PhD (1991) degrees in physics from The University of Chicago. Following post-doc training in medical imaging from 1992-1994 in the Department of Radiology at The University of Chicago, he was appointed as an Assistant Professor of Radiology before being promoted to Associate Professor and Professor of Radiology in 2001 and 2006.

Professor Pan’s research centers on physics, algorithms, and engineering underpinning tomographic imaging and its biomedical and clinical applications. He and his laboratory have conducted research on advanced theory and algorithms for conventional and spectral computed tomography (CT), positron emission tomography (PET), single-photo-emission computed tomography (SPECT), and tomosynthesis especially digital breast tomosynthesis (DBT) and digital lung tomosynthesis (DLT). In collaborating with leading researchers in the field, he and his team have worked on magnetic resonance imaging (MRI) and have also investigated emerging imaging techniques, including electron-paramagnetic resonance imaging (EPRI), phase-contrast CT, and photo-acoustic tomography (PAT), among others. In recent years, he and his team have developed vigorous interest/effort in translating theoretical concepts and methods to biomedical application work that includes developing innovative hardware systems and workflows, enabled by advanced algorithms, with a strong emphasis on the relevance and impact of imaging technological solutions tailored to specific applications of biomedical and/or clinical significance, and have established continuous, close clinical and industrial collaboration and developed robust translational projects to facilitate this effort. Dr. Pan is a Fellow of AAPM, AIMBE, IAMBE, IEEE, OSA, and SPIE."

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Featured Articles

IEEE Transactions on

Biomedical Engineering

MAY 2021
VOLUME 68
NUMBER 5
IEBEAX
68
TBME, Volume 68, Issue 5, May 2021
Development and Characterization of a Non-Thermal Plasma Source for Therapeutic Treatments
A non−thermal plasma (NTP) system constituted by a radiofrequency generator directly coupled to a treatment probe is described. The NTP generated was analyzed and characterized to determine a plasma safety profile and a spreading technique to be used on heat−sensitive matter. When NTP interacts with surrounding air particles produces reactive oxygen and nitrogen species that exhibit bactericidal and antiseptic effects due to their strong biochemical reactivity. Afterward, the NTP source was validated through bacterial deactivation trials, biological tests and promoting and in vivo wound closure performed in mice. NTP source demonstrated faster wound healing than that performed with conventional treatments... Read more
Rapid impedance spectroscopy for monitoring tissue impedance, temperature, and treatment outcome during electroporation-based therapies
Electroporation-based therapies (EBT) employ high voltage pulsed electric fields to permeabilize tumor tissue; this results in a detectable impedance change. Impedance characterization with a potentiostat is limited by acquisition time (~10s) as this timeframe is larger than pulse periods used with EBTs (~1s). Here, we develop a rapid electrical impedance spectroscopy (EIS) method for impedance characterization (<1s) of electroporation and thermal effects during irreversible electroporation. A biphasic rectangular chirp signal allows for impedance measurements between 1.8 kHz – 4.93 MHz. For the first time, we show impedance analysis at high frequencies (~1 MHz) can delineate thermal effects from electroporation effects... Read more
Fast EEG-based decoding of the directional focus of auditory attention using common spatial patterns
Current hearing devices lack information about the sound source a user attends to when there are multiple speakers. Auditory attention decoding (AAD) algorithms, which decode the auditory attention from brain signals, solve this problem and inform the hearing device about the to-be-enhanced speaker. While current AAD algorithms typically require an EEG buffer of 10s, leading to long delays, we present a new fast and accurate AAD algorithm that decodes the spatial focus of auditory attention in 1s using common spatial pattern filtering... Read more
Distortion of the Intracranial Pressure Waveform by Extraventricular Drainage System
The EVD-based pressure measurement occurs at the distal end of fluid filled elastic tubing that may itself act as a filter and distort the waveform. While the frequency response of arterial catheter systems has been studied extensively to understand their transfer function characteristics for detailed waveform analysis of the arterial blood pressure wavelet, the degree to which the EVD and associated drainage system distort the ICP waveform has not been investigated systematically, yet... Read more
Learning Multiparametric Biomarkers for Assessing MR-Guided Focused Ultrasound Treatment of Malignant Tumors
A significant challenge for noninvasive MR-guided focused ultrasound (MRgFUS) treatment is assessing the viability of treated tissue during and immediately after MRgFUS procedures. Current clinical assessment uses contrast agents that prevent continuing MRgFUS treatment if tumor coverage is inadequate. This work presents a novel, noncontrast, learned multiparametric MR biomarker that can be used during treatment for iterative assessment with inhibiting treatment continuation. Trained using a novel volume-conserving registration algorithm, the presented noncontrast biomarker outperformed the current clinical standard on a VX2 rabbit tumor model. Details on the registration and deep learning model are included... Read more
Teleoperation of an ankle-foot prosthesis with a wrist exoskeleton
This work aims to mimic sensorimotor control pathways disrupted after amputation with a system that allows a user to teleoperate their ankle-foot prosthesis with a wrist exoskeleton while receiving augmented sensory feedback. We present a novel wrist exoskeleton design and two control strategies that dictate ankle prosthesis behavior based on wrist input. We validate all system components with benchtop testing and demonstrate that one individual with transtibial amputation can accurately command desired wrist trajectories while walking. Systems like this have the potential to provide insight into human motor control and improve functional gait metrics for people with lower-limb amputation... Read more