Recent Articles

Heart-Lung Interactions During Mechanical Ventilation: Analysis via a Cardiopulmonary Simulation Model 150 150 IEEE Open Journal of Engineering in Medicine and Biology (OJEMB)

Heart-Lung Interactions During Mechanical Ventilation: Analysis via a Cardiopulmonary Simulation Model

Heart-lung interaction mechanisms are generally not well understood. Mechanical ventilation, for example, accentuates such interactions and could compromise cardiac activity. Thereby, assessment of ventilation-induced changes in cardiac function is considered…

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RADxSM Tech: A New Paradigm for MedTech Development Overview of This Special Section 2000 582 IEEE Open Journal of Engineering in Medicine and Biology (OJEMB)

RADxSM Tech: A New Paradigm for MedTech Development Overview of This Special Section
Author(s)3: Steven Schachter, John A. Parrish

The papers in this special section focuses on the major interrelated components of Rapid Acceleration of Diagnostics (RADxSM) Tech, a National Institutes of Health (NIH)-funded program launched on April 29,…

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Untargeted Large Volume Hyperthermia Reduces Tumor Drug Uptake From Thermosensitive Liposomes 150 150 IEEE Open Journal of Engineering in Medicine and Biology (OJEMB)

Untargeted Large Volume Hyperthermia Reduces Tumor Drug Uptake From Thermosensitive Liposomes
Author(s)3: Krishna K. Ramajayam, A. Marissa Wolfe, Anjan Motamarry, Georges J. Nahhas, John Yost, Michael J. Yost, Dieter Haemmerich

Goal: The impact of hyperthermia (HT) method on tumor drug uptake with thermosensitive liposomes (TSL) is not well understood. Methods: We created realistic three-dimensional (3-D) computer models that simulate TSL-encapsulated…

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A Novel Approach to Generate a Virtual Population of Human Coronary Arteries for In Silico Clinical Trials of Stent Design 150 150 IEEE Open Journal of Engineering in Medicine and Biology (OJEMB)

A Novel Approach to Generate a Virtual Population of Human Coronary Arteries for In Silico Clinical Trials of Stent Design
Author(s)3: Dimitrios S. Pleouras, Antonis I. Sakellarios, George Rigas, Georgia Karanasiou, Panagiota Tsompou, Gianna Karanasiou, Vassiliki Kigka, Savvas Kyriakidis, Vasileios C. Pezoulas, George Gois, Nikolaos Tachos, Aidonis Ramos, Gualtiero Pelosi, Silvia Rocchiccioli, Lampros K. Michalis, Dimitrios I. Fotiadis

Goal: To develop a cardiovascular virtual population using statistical modeling and computational biomechanics. Methods: A clinical data augmentation algorithm is implemented to efficiently generate virtual clinical data using a real…

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Non-Invasive Cardiac and Respiratory Activity Assessment From Various Human Body Locations Using Bioimpedance 150 150 IEEE Open Journal of Engineering in Medicine and Biology (OJEMB)

Non-Invasive Cardiac and Respiratory Activity Assessment From Various Human Body Locations Using Bioimpedance
Author(s)3: Kaan Sel, Deen Osman, Roozbeh Jafari

Objective: Bioimpedance sensing is a powerful technique that measures the tissue impedance and captures important physiological parameters including blood flow, lung movements, muscle contractions, body fluid shifts, and other cardiovascular…

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Machine Learning Approach for Biopsy-Based Identification of Eosinophilic Esophagitis Reveals Importance of Global features 150 150 IEEE Open Journal of Engineering in Medicine and Biology (OJEMB)

Machine Learning Approach for Biopsy-Based Identification of Eosinophilic Esophagitis Reveals Importance of Global features
Author(s)3: Tomer Czyzewski, Nati Daniel, Mark Rochman, Julie M. Caldwell, Garrett A. Osswald, Margaret H. Collins, Marc E. Rothenberg, Yonatan Savir

Eosinophilic esophagitis (EoE) is an allergic inflammatory condition characterized by eosinophil accumulation in the esophageal mucosa. EoE diagnosis includes a manual assessment of eosinophil levels in mucosal biopsies–a time-consuming, laborious…

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Comprehensive Assessment of Fine-Grained Wound Images Using a Patch-Based CNN With Context-Preserving Attention 150 150 IEEE Open Journal of Engineering in Medicine and Biology (OJEMB)

Comprehensive Assessment of Fine-Grained Wound Images Using a Patch-Based CNN With Context-Preserving Attention
Author(s)3: Ziyang Liu, Emmanuel Agu, Peder Pedersen, Clifford Lindsay, Bengisu Tulu, Diane Strong

Chronic wounds affect 6.5 million Americans. Wound assessment via algorithmic analysis of smartphone images has emerged as a viable option for remote assessment. Methods: We comprehensively score wounds based on…

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Reducing COVID-19 Cases and Deaths by Applying Blockchain in Vaccination Rollout Management 150 150 IEEE Open Journal of Engineering in Medicine and Biology (OJEMB)

Reducing COVID-19 Cases and Deaths by Applying Blockchain in Vaccination Rollout Management
Author(s)3: Jorge Medina, Roberto Cessa-Rojas, Vatcharapan Umpaichitra

Because a fast vaccination rollout against coronavirus disease 2019 (COVID-19) is critical to restore daily life and avoid virus mutations, it is tempting to have a relaxed vaccination-administration management system.…

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A Framework for Efficient N-Way Interaction Testing in Case/Control Studies With Categorical Data 150 150 IEEE Open Journal of Engineering in Medicine and Biology (OJEMB)

A Framework for Efficient N-Way Interaction Testing in Case/Control Studies With Categorical Data
Author(s)3: Aristos Aristodimou, Athos Antoniades, Efthimios Dardiotis, Eleni M. Loizidou, George M. Spyrou, Christina Votsi, Kyproula Christodoulou, Marios Pantzaris, Nikolaos Grigoriadis, Georgios M. Hadjigeorgiou, Theodoros Kyriakides, Constantinos S. Pattichis

Most common diseases are influenced by multiple gene interactions and interactions with the environment. Performing an exhaustive search to identify such interactions is computationally expensive and needs to address the…

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