Articles

RADxSM Tech: A New Paradigm for MedTech Development Overview of This Special Section

Author(s)3: Steven Schachter, John A. Parrish
RADxSM Tech: A New Paradigm for MedTech Development Overview of This Special Section 2000 582 IEEE Open Journal of Engineering in Medicine and Biology (OJEMB)

The papers in this special section focuses on the major interrelated components of Rapid Acceleration of Diagnostics (RADxSM) Tech, a National Institutes of Health (NIH)-funded program launched on April 29,…

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Untargeted Large Volume Hyperthermia Reduces Tumor Drug Uptake From Thermosensitive Liposomes

Author(s)3: Krishna K. Ramajayam, A. Marissa Wolfe, Anjan Motamarry, Georges J. Nahhas, John Yost, Michael J. Yost, Dieter Haemmerich
Untargeted Large Volume Hyperthermia Reduces Tumor Drug Uptake From Thermosensitive Liposomes 150 150 IEEE Open Journal of Engineering in Medicine and Biology (OJEMB)

Goal: The impact of hyperthermia (HT) method on tumor drug uptake with thermosensitive liposomes (TSL) is not well understood. Methods: We created realistic three-dimensional (3-D) computer models that simulate TSL-encapsulated…

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A Novel Approach to Generate a Virtual Population of Human Coronary Arteries for In Silico Clinical Trials of Stent Design

Author(s)3: Dimitrios S. Pleouras, Antonis I. Sakellarios, George Rigas, Georgia Karanasiou, Panagiota Tsompou, Gianna Karanasiou, Vassiliki Kigka, Savvas Kyriakidis, Vasileios C. Pezoulas, George Gois, Nikolaos Tachos, Aidonis Ramos, Gualtiero Pelosi, Silvia Rocchiccioli, Lampros K. Michalis, Dimitrios I. Fotiadis
A Novel Approach to Generate a Virtual Population of Human Coronary Arteries for In Silico Clinical Trials of Stent Design 150 150 IEEE Open Journal of Engineering in Medicine and Biology (OJEMB)

Goal: To develop a cardiovascular virtual population using statistical modeling and computational biomechanics. Methods: A clinical data augmentation algorithm is implemented to efficiently generate virtual clinical data using a real…

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Non-Invasive Cardiac and Respiratory Activity Assessment From Various Human Body Locations Using Bioimpedance

Author(s)3: Kaan Sel, Deen Osman, Roozbeh Jafari
Non-Invasive Cardiac and Respiratory Activity Assessment From Various Human Body Locations Using Bioimpedance 150 150 IEEE Open Journal of Engineering in Medicine and Biology (OJEMB)

Objective: Bioimpedance sensing is a powerful technique that measures the tissue impedance and captures important physiological parameters including blood flow, lung movements, muscle contractions, body fluid shifts, and other cardiovascular…

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Machine Learning Approach for Biopsy-Based Identification of Eosinophilic Esophagitis Reveals Importance of Global features

Author(s)3: Tomer Czyzewski, Nati Daniel, Mark Rochman, Julie M. Caldwell, Garrett A. Osswald, Margaret H. Collins, Marc E. Rothenberg, Yonatan Savir
Machine Learning Approach for Biopsy-Based Identification of Eosinophilic Esophagitis Reveals Importance of Global features 150 150 IEEE Open Journal of Engineering in Medicine and Biology (OJEMB)

Eosinophilic esophagitis (EoE) is an allergic inflammatory condition characterized by eosinophil accumulation in the esophageal mucosa. EoE diagnosis includes a manual assessment of eosinophil levels in mucosal biopsies–a time-consuming, laborious…

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Comprehensive Assessment of Fine-Grained Wound Images Using a Patch-Based CNN With Context-Preserving Attention

Author(s)3: Ziyang Liu, Emmanuel Agu, Peder Pedersen, Clifford Lindsay, Bengisu Tulu, Diane Strong
Comprehensive Assessment of Fine-Grained Wound Images Using a Patch-Based CNN With Context-Preserving Attention 150 150 IEEE Open Journal of Engineering in Medicine and Biology (OJEMB)

Chronic wounds affect 6.5 million Americans. Wound assessment via algorithmic analysis of smartphone images has emerged as a viable option for remote assessment. Methods: We comprehensively score wounds based on…

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Reducing COVID-19 Cases and Deaths by Applying Blockchain in Vaccination Rollout Management

Author(s)3: Jorge Medina, Roberto Cessa-Rojas, Vatcharapan Umpaichitra
Reducing COVID-19 Cases and Deaths by Applying Blockchain in Vaccination Rollout Management 150 150 IEEE Open Journal of Engineering in Medicine and Biology (OJEMB)

Because a fast vaccination rollout against coronavirus disease 2019 (COVID-19) is critical to restore daily life and avoid virus mutations, it is tempting to have a relaxed vaccination-administration management system.…

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A Framework for Efficient N-Way Interaction Testing in Case/Control Studies With Categorical Data

Author(s)3: Aristos Aristodimou, Athos Antoniades, Efthimios Dardiotis, Eleni M. Loizidou, George M. Spyrou, Christina Votsi, Kyproula Christodoulou, Marios Pantzaris, Nikolaos Grigoriadis, Georgios M. Hadjigeorgiou, Theodoros Kyriakides, Constantinos S. Pattichis
A Framework for Efficient N-Way Interaction Testing in Case/Control Studies With Categorical Data 150 150 IEEE Open Journal of Engineering in Medicine and Biology (OJEMB)

Most common diseases are influenced by multiple gene interactions and interactions with the environment. Performing an exhaustive search to identify such interactions is computationally expensive and needs to address the…

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Stand-Up, Squat, Lunge, and Walk With a Robotic Knee and Ankle Prosthesis Under Shared Neural Control

Author(s)3: Grace R. Hunt, Sarah Hood, Tommaso Lenzi
Stand-Up, Squat, Lunge, and Walk With a Robotic Knee and Ankle Prosthesis Under Shared Neural Control 150 150 IEEE Open Journal of Engineering in Medicine and Biology (OJEMB)

Emerging robotic knee and ankle prostheses present an opportunity to restore the biomechanical function of missing biological legs, which is not possible with conventional passive prostheses. However, challenges in coordinating…

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Cgmquantify: Python and R Software Packages for Comprehensive Analysis of Interstitial Glucose and Glycemic Variability from Continuous Glucose Monitor Data

Author(s)3: Brinnae Bent, Maria Henriquez, Jessilyn P. Dunn
Cgmquantify: Python and R Software Packages for Comprehensive Analysis of Interstitial Glucose and Glycemic Variability from Continuous Glucose Monitor Data 150 150 IEEE Open Journal of Engineering in Medicine and Biology (OJEMB)

Continuous glucose monitoring (CGM) is commonly used in Type 1 diabetes management by clinicians and patients and in diabetes research to understand how factors of longitudinal glucose and glucose variability…

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