Optical cryoimaging Archives - IEEE Journal of Translational Engineering in Health and Medicine (JTEHM)

June 30, 2016

Optical Cryoimaging Reveals a Heterogeneous Distribution of Mitochondrial Redox State in ex vivo Guinea Pig Hearts and its Alteration during Ischemia and Reperfusion

Author(s)3: Mahsa Ranji, Mohammad Masoudi Motlagh, Fahimeh Salehpour, Reyhaneh Sepehr, James S. Heisner, Ranjan K Dash, Amadou KS Camara

Optical Cryoimaging Reveals a Heterogeneous Distribution of Mitochondrial Redox State in ex vivo Guinea Pig Hearts and its Alteration during Ischemia and Reperfusion https://www.embs.org/jtehm/wp-content/uploads/sites/17/2016/06/optical-cryoimaging.jpg 780 435 IEEE Journal of Translational Engineering in Health and Medicine (JTEHM) IEEE Journal of Translational Engineering in Health and Medicine (JTEHM) //www.embs.org/jtehm/wp-content/uploads/sites/17/2022/06/ieee-jtehm-logo2x.png June 30, 2016 March 4, 2022

Objective: Oxidation of substrates to generate ATP in mitochondria is mediated by redox reactions of NADH and FADH2. Cardiac ischemia and reperfusion (IR) injury compromises mitochondrial oxidative phosphorylation. We hypothesize…