microfluidic

For suspected serious bacterial infection in infants, ampicillin administration is a standard treatment (left panel). However, patients with a β-lactamase positive infection may be resistant to this treatment. As delays in effective treatment are correlated with poor patient outcome, rapid identification of this situation is desirable. The assay presented here (right panel) rapidly detects β-lactamase positive infections and identifies ineffective antibiotics in less than 20 minutes, allowing clinicians to make informed treatment decisions at the point of care

Guiding Empiric Treatment for Serious Bacterial Infections via Point of Care B-Lactamase Characterization

Author(s): Akilan Palaniswami, Shazia Khan, Sultan Siebel Erdem, Tayyaba Hasan
Guiding Empiric Treatment for Serious Bacterial Infections via Point of Care B-Lactamase Characterization 780 656 IEEE Journal of Translational Engineering in Health and Medicine (JTEHM)

For suspected serious bacterial infection in infants, ampicillin administration is a standard treatment (left panel). However, patients with a β-lactamase positive infection may be resistant to this treatment. As delays…

read more