Accumulation of excess air and water in the lungs leads to breakdown of respiratory function and is a common cause of patient hospitalization. Compact and non-invasive methods to detect the changes in lung fluid accumulation can allow physicians to assess patients’ respiratory conditions. In this paper, an acoustic transducer and a digital stethoscope system are proposed as a targeted solution for this clinical need. Alterations in the structure of the lungs lead to measurable changes which can be used to assess lung pathology. We standardize this procedure by sending a controlled signal through the lungs of six healthy subjects and six patients with lung disease. We extract mel-frequency cepstral coefficients and spectroid audio features, commonly used in classification for music retrieval, to characterize subjects as healthy or diseased. Using the K -nearest neighbors algorithm, we demonstrate 91.7% accuracy in distinguishing between healthy subjects and patients with lung pathology.