Continuous temperature monitoring in high-risk patients can enable healthcare providers to remotely track patients’ temperatures, promptly detect fevers and timely intervene to improve clinical outcomes. We evaluated if a novel wearable, continuous temperature monitor (Verily Patch) can reliably estimate body temperature and early detect fevers in an outpatient setting in patients at a high risk of febrile neutropenia (FN) who recently underwent chemotherapy and autologous stem cell transplantation (ASCT). Methods: 86 patients at a high risk for FN were prospectively enrolled at Mayo Clinic, MN. Patients wore the device in their axilla region for 7 days post ASCT and recorded self-measured oral temperatures every 3 hours. Patients were also followed using clinical standard-of-care procedures with daily oral temperature assessment. The clinic-and patientassessed oral temperatures were used to develop and evaluate Verily Patch’s body temperature and early fever detection algorithms using a K-fold cross-validation approach. Results: The Verily Patch reliably measured body temperatures with an error of 0.35±0.88°F in comparison to clinic-and patient-assessed oral temperatures. The sensitivity and specificity of the patch in detecting clinic-assessed fever episodes was 90.2% and 87.8%. The patch detected 14.3 times the number of clinic-assessed fever episodes with a median lead time of 4.3 hours. Conclusion: Patient self-monitoring of temperature and fever incidents suffers from low accuracy and is impractical for extended periods of time. Continuous temperature monitoring by a wearable device (such as Verily Patch) has the potential to overcome these challenges resulting in better patient clinical outcomes and more cost-effective care.
A Novel Wearable Device for Continuous Temperature Monitoring & Fever Detection https://www.embs.org/jtehm/wp-content/themes/movedo/images/empty/thumbnail.jpg 150 150 IEEE Journal of Translational Engineering in Health and Medicine (JTEHM) //www.embs.org/jtehm/wp-content/uploads/sites/17/2022/06/ieee-jtehm-logo2x.png