Dr. Sameshima graduated in Electrical Engineering (1979) and Medicine (1985) from the University of São Paulo. He received his Ph. D. degree in Neurophysiology from the same University (1992), and post-doctoral training in System Neuroscience at the University of California at San Francisco (1994). He is a co-founding member of the Discipline of Medical Informatics (1986), and holds an Associate Professorship at the Department of Radiology & Oncology at the Faculty of Medicine of the University of São Paulo. His main research themes are the study of neural plasticity, cognitive function and information processing aspects of mammalian brain assessed through behavioral, electrophysiological and computational neuroscience protocols. To functionally characterize collected multichannel neural activities and correlate them to animal or human behavior and cognitive function, he is pursuing and developing robust and clinically useful methods and measures for brain dynamics staging and neural connectivity inferences, for which he co-introduced the concept of partial directed coherence. At the graduate level, he teaches courses in neural plasticity and learning, electrophysiological methodology in the study of cognitive functions, and quantitative analysis of biomedical data. He is native of Bonotsu-cho (now part of Minamisatsuma-shi), Kagoshima Prefecture, Japan.