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Special Issue on AI-driven Informatics, Sensing, Imaging and Big Data Analytics for Fighting the COVID-19 Pandemic
Special Issue on AI-driven Informatics, Sensing, Imaging and Big Data Analytics for Fighting the COVID-19 Pandemic IEEE EMBS

In this issue, vol. 26, issue 4, April 2022, 2 papers are published related to the Special Issue on AI-driven Informatics, Sensing, Imaging and Big Data Analytics for Fighting the…

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Special Issue on Data Analytics for Public Health Care
Special Issue on Data Analytics for Public Health Care 150 150 IEEE EMBS

In this issue, vol. 26, issue 4, April 2022, 7 papers are published related to the Special Issue on Data Analytics for Public Health care. Please click here to view…

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Automatic Artificial Pancreas Systems Using an Intelligent Multiple-Model PID Strategy
Automatic Artificial Pancreas Systems Using an Intelligent Multiple-Model PID Strategy 150 150 IEEE EMBS

In this paper, an individualized intelligent multiple-model technique is proposed to design automatic artificial pancreas (AP) systems for the glycemic regulation of type 1 diabetic patients. At first, using the…

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Sensitivity Analysis Highlights the Importance of Accurate Head Models for Electrical Impedance Tomography Monitoring of Intracerebral Hemorrhagic Stroke
Sensitivity Analysis Highlights the Importance of Accurate Head Models for Electrical Impedance Tomography Monitoring of Intracerebral Hemorrhagic Stroke IEEE EMBS
In this study, we investigate the role of accurate head modeling in electrical impedance tomography (EIT) monitoring of intracerebral hemorrhagic stroke. We compared anatomically detailed six-layer and simplified three-layer finite element models and computed and visualized scalp potentials, lead fields and sensitivity distributions with various perturbations. In addition, inverse imaging was examined with selected cases. Our results show that detailed anatomy and realistic tissue conductivities have significant effect on the simulated measurements, the sensitivities and the EIT images reconstructed from the simulated measurement data. We conclude it’s important to consider the anatomical details such as cerebrospinal fluid in EIT research. read more

Estimating Ground Reaction Force and Center of Pressure Using Low-Cost Wearable Devices
Author(s)3: Brandon Oubre, Sunghoon Ivan Lee
Estimating Ground Reaction Force and Center of Pressure Using Low-Cost Wearable Devices 690 388 IEEE EMBS
Ambulatory monitoring of ground reaction force (GRF) and plantar center of pressure (CoP) could improve management of health conditions that impair mobility. This work presents a system consisting of 1) an insole instrumented with six force-sensitive resistors and 2) a string-based knee angle sensor. Supervised machine learning models estimated weight-normalized GRF and shoe size-normalized CoP, which were re-scaled to obtain GRF and CoP. Normalized models accurately estimated GRF and CoP despite deficiencies in force sensor data. Ambulatory use of the proposed system could enable objective, longitudinal monitoring of severity and progression for a variety of health conditions. read more

Gamma Power of Electroencephalogram Arousal is Modulated by Respiratory Event Type and Severity in Obstructive Sleep Apnea
Gamma Power of Electroencephalogram Arousal is Modulated by Respiratory Event Type and Severity in Obstructive Sleep Apnea IEEE EMBS
This work investigated breathing obstruction-related arousal intensity via high-frequency spectral content in nocturnal electroencephalogram (EEG). Gamma band (30–40 Hz) power in EEG was studied during arousals caused by different respiratory events in 869 patients with suspected obstructive sleep apnea (OSA). Arousal gamma power was higher in deeper sleep and increased alongside the respiratory event severity. As elevated gamma activity could indicate a greater shift towards wakefulness, the results illustrate that the magnitude of sleep disruption might vary depending on the respiratory event characteristics. These findings can bring more insight into respiratory event-related sleep fragmentation in OSA severity assessment. read more

Flexible hybrid integration enabled on-skin electronics for wireless monitoring of electrophysiology and motion
Author(s)3: Jun Zhao
Flexible hybrid integration enabled on-skin electronics for wireless monitoring of electrophysiology and motion IEEE EMBS
This work reports flexible hybrid integration strategies which endow the on-skin electronic system with advantages of high integration density of electric components, facile fabrication schemes, high stretchability and reliability, and soft and conformal interfaces with human skin. Based on these strategies, an on-skin flexible hybrid electronic system (FHES) is fabricated to collect human electrocardiogram (ECG) and acceleration data, wirelessly transmit and display the data in real time on a mobile phone application through Bluetooth communication. This on-skin system has great potential for applications in wearable health monitoring and physical training. read more

Acoustic holograms for bilateral blood-brain barrier opening in a mouse model
Author(s)3: Elisa E. Konofagou
Acoustic holograms for bilateral blood-brain barrier opening in a mouse model IEEE EMBS
Microbubble-enhanced focused ultrasound (FUS) allows the blood-brain barrier opening (BBBO) for drug delivery into the brain. However, single-element FUS technologies do not allow high-resolution, multi-focal, simultaneous targeting, in addition to distortion of the focused beam due to skull aberrations. In this work, we present the first preclinical BBBO application of acoustic holograms in mice. A 3D-printed hologram coupled to a single-element focused transducer produced two symmetric foci while compensating for the skull aberrations. T1-weighted MRI showed BBBO at two quasi-spherical spots. This work demonstrates the feasibility of hologram-assisted BBBO for low-cost and highly-localized drug delivery in a mouse brain. read more

Disrupting the Normal Routine
Author(s)3: Art Johnson
Disrupting the Normal Routine 150 150 IEEE EMBS
My secretary at the University of Maryland labeled it Working Away From the Office (WAFO). It was my routine to stay home on Wednesdays and write papers, author books, make teaching plans, or grade papers and reports. I would be in my office Monday, Tuesday, Thursday, and Friday, but everyone in our department soon got used to my absence on Wednesday. read more

New Horizons: From Vision to Impact
Author(s)3: Metin Akay
New Horizons: From Vision to Impact 150 150 IEEE EMBS
Over the past two years, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), and the associated coronavirus disease (COVID-19), have greatly impacted our lives. This pandemic has revealed how our health care systems were not prepared for this major challenge, especially with respect to treatment, rapid diagnosis, and tracking, as well as limited hospital equipment, staff members, and resources. read more
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