Axel Krieger

Associated articles

TBME, Featured Articles
A Biocompatible Near-Infrared 3D Tracking System
A fundamental challenge in soft-tissue surgery is that target tissue moves and deforms, becomes occluded by blood or other tissue, and is difficult to differentiate from surrounding tissue. To overcome these problems, we developed biocompatible near-infrared fluorescent (NIRF) markers with... Read more
TBME, Featured Articles
Semi-Automatic Planning and Three-Dimensional Electrospinning of Patient-Specific Grafts for Fontan Surgery
This work aims to develop a semi-automatic tissue engineered vascular graft (TEVG) planning method for designing and 3D-printing hemodynamically optimized Fontan TEVGs. We present a computation framework by parameterizing Fontan grafts to explore patient-specific vascular graft design space and search for optimal designs. We employed nonlinear constrained optimization technique to minimize indexed power loss of Fontan grafts while keeping hepatic flow distribution (HFD) and percentage of abnormal wall shear stress (%WSS) within clinically acceptable thresholds. Our work significantly reduces the collaborative effort and turnaround time between clinicians and engineering teams for designing patient-specific hemodynamically optimized TEVGs... Read more