Time-of-flight (TOF) positron-emission tomography (PET) has increasingly been adopted as an important quantitative imaging tool in basic and clinical applications. Improving image quality via advanced image reconstruction methods remains an area of active interest. In particular, it is of practical...
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TOF - PET has increasingly been adopted as an important quantitative imaging tool in basic and clinical applications. We investigate an optimization-based image reconstruction (OBIR) method for the purposes of improving image quality and enabling reconstruction from low-count data. Our study indicates the OBIR method has the potential to enhance spatial/contrast resolution, signal-to-noise ratio, and axial volume coverage and to reduce false lesions over images reconstructed with the clinical TOF-PET algorithm...
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