Amadou KS Camara
Amadou KS Camara is a Professor in the Department of Anesthesiology at the Medical College of Wisconsin (MCW). He received his Ph.D. degree in Renal and Cardiovascular Physiology from the Department of Physiology at MCW in May of 1995. After his postdoctoral training in cardiac electrophysiology in the Department of Anesthesiology in 1999 at MCW, he joined the faculty and shortly became interested in mitochondrial biology. He has published more than 85 articles in peer-reviewed scientific journals and several book chapters, with the vast majority of his publications focused on mitochondrial biology and cardiac pathophysiology. Today, he continues to devote much of his research on mitochondria and its role in the etiology of heart disease, specifically, delving into the molecular mechanisms of changes in mitochondrial protein functions during ischemic stress and the impact on organ dysfunction.
JTEHM, Articles, Published ArticlesOptical Cryoimaging Reveals a Heterogeneous Distribution of Mitochondrial Redox State in ex vivo Guinea Pig Hearts and its Alteration during Ischemia and Reperfusion
Mahsa Ranji, Mohammad Masoudi Motlagh, Fahimeh Salehpour, Reyhaneh Sepehr, James S. Heisner, Ranjan K Dash, Amadou KS Camara
Objective: Oxidation of substrates to generate ATP in mitochondria is mediated by redox reactions of NADH and FADH2. Cardiac ischemia and reperfusion (IR) injury compromises mitochondrial oxidative phosphorylation. We hypothesize that IR alters the metabolic heterogeneity of mitochondrial redox state... Read more
Posted on 30 JUN 2016