IEEE Open Journal of Engineering in Medicine and Biology

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Ultrasound Based Planning and Navigation for Non-Anatomical Liver Resections – An Ex-Vivo Study
Non-anatomical resections of liver tumors can be very challenging as the surgeon cannot use anatomical landmarks on the liver surface or in the ultrasound image for guidance. This makes it difficult to achieve negative resection margins (R0) and still preserve... Read more
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Ultrasound Stimulations Induce Prolonged Depolarization and Fast Action Potentials in Leech Neurons
Ultrasound (US) stimulation carries the promise of a selective, reversible, and non-invasive modulation of neural activity without the need for genetic manipulation of neural structures. However, the mechanisms of US-induced generation of action potentials (APs) are still unclear. Methods: Here... Read more
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3D Ultrasound Imaging of Residual Limbs With Camera-Based Motion Compensation
      Ultrasound is a cost-effective, readily available, and non-ionizing modality for musculoskeletal imaging. Though some research groups have pursued methods that involve submerging the transducer and imaged body segment into a water bath, many limitations remain in regards to acquiring an... Read more
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Gait and Dynamic Balance Sensing Using Wearable Foot Sensors
    Remote monitoring of gait performance offers possibilities for objective evaluation, and tackling impairment in motor ability, gait, and balance in populations such as elderly, stroke, multiple sclerosis, Parkinson’s, etc. This requires a wearable and unobtrusive system capable of estimating ambulatory... Read more
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Shear Waves Reveal Viscoelastic Changes in Skeletal Muscles after Hemispheric Stroke
    We investigated alterations in material properties such as elasticity and viscoelasticity of stroke-affected muscles using ultrasound induced shear waves and mechanical models. We used acoustic radiation force to generate shear waves along fascicles of biceps muscles and measured their propagation... Read more
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Screening for Cognitive Impairment by Model Assisted Cerebral Blood Flow Estimation
Alzheimer’s disease is a progressive and debilitating neurodegenerative disease; one in ten people aged 65 and older have it. As there is no cure for Alzheimer’s disease, early diagnosis is crucial so that mitigating treatments can be initiated as soon... Read more
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FPGA Implementation of the Coupled Filtering Method and the Affine Warping Method
In ultrasound image analysis, the speckle tracking methods are widely applied to study the elasticity of body tissue. However, “feature-motion decorrelation” still remains as a challenge for the speckle tracking methods. Recently, a coupled filtering method and an affine warping... Read more
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Use of Model Predictive Control and Artificial Neural Networks to Optimize the Ultrasonic Release of a Model Drug From Liposomes
The use of echogenic liposomes to deliver chemotherapeutic agents for cancer treatment has gained wide recognition in the last 20 years. Cancerous cells can develop multiple drug resistance (MDR), in part, due to the drop in concentration of chemotherapeutic agents... Read more