Transactions on NanoBioscience
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Identification Exon Skipping Events From High-Throughput RNA Sequencing Data
The emergence of next-generation high-throughput RNA sequencing (RNA-Seq) provides tremendous opportunities for researchers to analyze alternative splicing on a genome-wide scale. However, accurate identification of alternative splicing events from RNA-Seq data has remained an unresolved challenge in next-generation sequencing (NGS)...
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Posted on 24 AUG 2015
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A Generalized dSpliceType Framework to Detect Differential Splicing and Differential Expression Events Using RNA-Seq
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Abstract
Transcriptomes are routinely compared in term of a list of differentially expressed genes followed by functional enrichment analysis. Due to the technology limitations of microarray, the molecular mechanisms of differential expression is poorly...
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Posted on 14 APR 2015