Transactions on NanoBioscience

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HapIso: An Accurate Method for the Haplotype- Specific Isoforms Reconstruction From Long Single-Molecule Reads
Sequencing of RNA provides the possibility to study an individual’s transcriptome landscape and determine allelic expression ratios. Single-molecule protocols generate multi-kilobase reads longer than most transcripts, allowing sequencing of complete haplotype isoforms. This allows partitioning the reads into two parental... Read more
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Nanoparticles for siRNA-Based Gene Silencing in Tumor Therapy
Gene silencing through RNA interference (RNAi) has emerged as a potential strategy in manipulating cancer causing genes by complementary base-pairing mechanism. Small interfering RNA (siRNA) is an important RNAi tool that has found significant application in cancer therapy. However due... Read more
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TargetM6A: Identifying N6-Methyladenosine Sites From RNA Sequences via Position-Specific Nucleotide Propensities and a Support Vector Machine
As one of the most ubiquitous post-transcriptional modifications of RNA, N6-methyladenosine ( m 6 A  ) plays an essential role in many vital biological processes. The identification of m 6 A  sites in RNAs is significantly important for both basic biomedical research and practical... Read more
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Heterogeneous Network Model to Infer Human Disease-Long Intergenic Non-Coding RNA Associations
ACCESS PAPER DATA READ FULL ARTICLE ON IEEE XPLORE Abstract With the knowledge of molecular biology it is highlighting that long non-coding RNAs (lncRNAs) play a critical role in many important biological processes, such as imprinting control, cell differentiation, immune responses, human diseases,... Read more