Transactions on NanoBioscience

Featured Articles
HapIso: An Accurate Method for the Haplotype- Specific Isoforms Reconstruction From Long Single-Molecule Reads
Serghei Mangul, Taegyun Harry Yang, Farhad Hormozdiari, Alexandra Marie Dainis, Elizabeth Tseng, Euan A. Ashley, Alex Zelikovsky, Eleazar Eskin
Sequencing of RNA provides the possibility to study an individual’s transcriptome landscape and determine allelic expression ratios. Single-molecule protocols generate multi-kilobase reads longer than most transcripts, allowing sequencing of complete haplotype isoforms. This allows partitioning the reads into two parental... Read more
Posted on 27 APR 2017
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Nanoparticles for siRNA-Based Gene Silencing in Tumor Therapy
Anish Babu, Ranganayaki Muralidharan, Narsireddy Amreddy, Meghna Mehta, Anupama Munshi, Rajagopal Ramesh
Gene silencing through RNA interference (RNAi) has emerged as a potential strategy in manipulating cancer causing genes by complementary base-pairing mechanism. Small interfering RNA (siRNA) is an important RNAi tool that has found significant application in cancer therapy. However due... Read more
Posted on 14 MAR 2017
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TargetM6A: Identifying N6-Methyladenosine Sites From RNA Sequences via Position-Specific Nucleotide Propensities and a Support Vector Machine
Guang-Qing Li, Zi Liu, Hong-Bin Shen, Dong-Jun Yu
As one of the most ubiquitous post-transcriptional modifications of RNA, N6-methyladenosine ( m 6 A  ) plays an essential role in many vital biological processes. The identification of m 6 A  sites in RNAs is significantly important for both basic biomedical research and practical... Read more
Posted on 26 DEC 2016
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Heterogeneous Network Model to Infer Human Disease-Long Intergenic Non-Coding RNA Associations
Gamage Upeksha Ganegoda, Min Li, Weiping Wang, Qilong Feng
ACCESS PAPER DATA READ FULL ARTICLE ON IEEE XPLORE Abstract With the knowledge of molecular biology it is highlighting that long non-coding RNAs (lncRNAs) play a critical role in many important biological processes, such as imprinting control, cell differentiation, immune responses, human diseases,... Read more
Posted on 14 APR 2015