IEEE Open Journal of Engineering in Medicine and Biology

Featured Articles
Ultrasound Stimulations Induce Prolonged Depolarization and Fast Action Potentials in Leech Neurons
Ultrasound (US) stimulation carries the promise of a selective, reversible, and non-invasive modulation of neural activity without the need for genetic manipulation of neural structures. However, the mechanisms of US-induced generation of action potentials (APs) are still unclear. Methods: Here... Read more
Articles, Published Articles
Implementation and Long-Term Evaluation of a Hearing Aid Supported Tinnitus Treatment using Notched Environmental Sounds
       Abstract Recent work has shown that sharp spectral edges in acoustic stimuli might have advantageous effects in the treatment of tonal tinnitus. In the course of this paper, we evaluate the long-term effects of spectrally notched hearing aids on the subjective... Read more
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Distortion Distribution of Neural Spike Train Sequence Matching with Optogenetics
Optogenetics, named “Breakthrough of the Decade” by Science Magazine, gives scientists the ability to directly control individual neurons with pulses of light. The technique involves genetic modification of neurons, causing them to express light-sensitive proteins called opsins. When exposed to... Read more
Articles, Published Articles
Low-Power and Low-Cost Dedicated Bit-Serial Hardware Neural Network for Epileptic Seizure Prediction System
  This paper presents results of using a simple bit-serial architecture as a method of designing an extremely low-power and low-cost neural network processor for epilepsy seizure prediction. The proposed concept is based on a novel bit-serial data processing unit (DPU)... Read more
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A Fast Algorithm for Analysis of Molecular Communication in Artificial Synapse
In this paper, we analyze molecular communications (MCs) in a proposed artificial synapse (AS), whose main difference from biological synapses (BSs) is that it is closed, i.e., transmitter molecules cannot diffuse out from AS. Such a setup has both advantages... Read more
Special Issue: BRAIN
Combined single neuron unit activity and local field potential oscillations in a human visual recognition memory task
Kucewicz, M.T., Berry, B.M., Bower, M.R., Cimbalnik, J., Svehlik, V., Stead, S.M., Worrell, G.A., Mayo Clinic, USA Current neurotechnologies typically probe only a limited range of the vast scale of human brain electrophysiological activities, focusing either on the micro-electrode recordings of... Read more
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Hierarchy of Neural Organization in the Embryonic Spinal Cord: Granger-Causality Graph Analysis of In Vivo Calcium Imaging Data
Abstract The recent development of genetically encoded calcium indicators enables monitoring in vivo the activity of neuronal populations. Most analysis of these calcium transients relies on linear regression analysis based on the sensory stimulus applied or the behavior observed. To estimate the basic properties of... Read more
Featured Articles
Suppression of Subthalamic Nucleus Activity by Micromagnetic Stimulation
Abstract Magnetic stimulation delivered via 0.5-mm diameter coils was recently shown to activate retinal neurons; the small coil size raises the possibility that micromagnetic stimulation (μMS) could underlie a new generation of implanted neural prosthetics. Such an approach has several inherent... Read more