IEEE Open Journal of Engineering in Medicine and Biology

Goal: We describe the relationship between mean arterial pressure (MAP) and glomerular filtration rate (GFR) since therapies affecting MAP can have large effects on kidney function. Methods: We developed a closed-loop, steady-state mechanistic model of the human kidney with a... Read more

Phillip J. Hendrickson, Gene J. Yu, Dong Song, and Theodore W. Berger, University of Southern California, USA Developing large-scale, quantitatively based models of neural systems has become a realizable goal in recent years, largely because of three major developments: (i) the accumulation... Read more

Conventional methods for estimating cardiopulmonary variables usually require complex gas analysers and the active co-operation of the patient. Therefore, they are not compatible with the crowded environment of the Intensive Care Unit (ICU) or operating theatre, where patient co-operation is... Read more