IEEE Transactions on Biomedical Engineering

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A Dual-Mode Large-Arrayed CMOS ISFET Sensor for Accurate and High-Throughput pH Sensing in Biomedical Diagnosis
The existing ion-sensitive field effect transistor (ISFET) based DNA sequencing detects hydrogen ions (H+) released during polymerization of DNA strands that are attached on microbeads. However, these microbeads are scattered into microwell array above the ISFET sensor with unknown distribution.... Read more