Transactions on NanoBioscience

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Development of an On-Chip Antibiotic Permeability Assay With Single Molecule Detection Capability
Electrophysiology is the method of choice to characterize membrane channels. In this paper, we demonstrate a patch pipette based simple miniaturization that allows performing conductance measurements on a planar lipid bilayer in a microfluidic channel. Membrane proteins were reconstituted into... Read more
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Axonal Channel Capacity in Neuro-Spike Communication
Novel nano-scale communication techniques are inspired by biological systems. Neuro-spike communication is an example of this communication paradigm which transfers vital information about external and internal conditions of the body through the nervous system. The analysis of this communication paradigm... Read more
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Analysis of Current Pulses in HeLa-Cell Permeabilization Due to High Voltage DC Corona Discharge
Corona discharges are commonly utilized for numerous practical applications, including bio-technological ones. The corona induced transfer of normally impermeant molecules into the interior of biological cells has recently been successfully demonstrated. The exact nature of the interaction of the corona... Read more
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An Effective Approach for Glycan Structure De Novo Sequencing From HCD Spectra
Mass spectrometry has become a widely used analytical technique for proteomics study because of its high throughput and sensitivity. Among those applications, a specific one is to characterize glycan structure. Glycosylation is a frequently occurred post-translational modification of proteins which... Read more